Detailed information of TA system TA181707

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2481904..2482084
• Replicon: chromosome
• Accession: NZ_CP064772
• Organism: Staphylococcus aureus strain TCH32767

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IXH55_RS12300
• Protein ID: WP_001801861.1
• Coordinates: 2481989..2482084 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2481904..2481961 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IXH55_RS12270 (IXH55_12205)	2477614..2477748	+	135	WP_001791797.1	hypothetical protein	-
IXH55_RS12275 (IXH55_12210)	2477912..2479468	+	1557	WP_000028669.1	type I restriction-modification system subunit M	-
IXH55_RS12280 (IXH55_12215)	2479461..2480690	+	1230	WP_000072627.1	restriction endonuclease subunit S	-
IXH55_RS12285 (IXH55_12220)	2481231..2481641	+	411	WP_001808705.1	IS21 family transposase	-
IXH55_RS12290 (IXH55_12225)	2481626..2481787	+	162	Protein_2384	transposase	-
IXH55_RS12295 (IXH55_12230)	2481765..2481866	-	102	WP_001792025.1	hypothetical protein	-
-	2481904..2481961	+	58	-	-	Antitoxin
IXH55_RS12300 (IXH55_12235)	2481989..2482084	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IXH55_RS12305 (IXH55_12240)	2482229..2483241	+	1013	Protein_2387	IS3 family transposase	-
IXH55_RS12310 (IXH55_12245)	2483439..2484011	-	573	WP_000414216.1	hypothetical protein	-
IXH55_RS12315 (IXH55_12250)	2484112..2484453	-	342	WP_000627540.1	DUF3969 family protein	-
IXH55_RS12320 (IXH55_12255)	2484494..2485120	-	627	WP_000669024.1	hypothetical protein	-
IXH55_RS12325 (IXH55_12260)	2485195..2486190	-	996	WP_000070642.1	DUF4352 domain-containing protein	-
IXH55_RS12330 (IXH55_12265)	2486271..2486921	-	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hlgA / lukD	2455950..2487679	31729

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T181707 WP_001801861.1 NZ_CP064772:c2482084-2481989 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T181707 NZ_CP086105:c459720-459376 [Ralstonia sp. RS650]
ATGGATGCTACCTTTATCGAGTTGCCGCCTTTTCAGAGGCTGCGGGAGCACTATCTCTCGGACGACGAGTACCGAGCGCT
CCAACAGGAACTGCTGGCCCGGCCGGACGCCGGCTACGTCATCAAGGGGACAGGTGGCCTACGCAAGCTGCGATTTTCGG
ACAAGCGGCGCGGCAAAGGTAAGCGCGGCGGTCTGCGCGTGATTGACTACCACTGGGATGGAGGCGGCCAATTCTGGATG
TTTGTCGTCTACGACAAGGGCGAGGCGGACGACCTTTCCAGCGACGAGCGCAAAGTGCTGGCACGGCTGTTGGAGCAGGA
AGTCAAGGCAAGGAGTGAGCGATGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT181707 NZ_CP064772:2481904-2481961 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin