Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1325418..1325947 Replicon chromosome
Accession NZ_CP064761
Organism Companilactobacillus futsaii strain Chongqingii CQ16Z1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag IT773_RS06385 Protein ID WP_195701102.1
Coordinates 1325684..1325947 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IT773_RS06380 Protein ID WP_162256560.1
Coordinates 1325418..1325681 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IT773_RS06365 1320418..1321803 - 1386 WP_195702065.1 group II intron reverse transcriptase/maturase -
IT773_RS06370 1322235..1323966 + 1732 Protein_1240 phosphoenolpyruvate synthase -
IT773_RS06375 1324016..1325278 - 1263 WP_195701101.1 replication-associated recombination protein A -
IT773_RS06380 1325418..1325681 + 264 WP_162256560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IT773_RS06385 1325684..1325947 + 264 WP_195701102.1 Txe/YoeB family addiction module toxin Toxin
IT773_RS06390 1326372..1327403 + 1032 WP_149029777.1 IS30 family transposase -
IT773_RS06395 1327912..1328178 + 267 WP_195701103.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
IT773_RS06400 1328171..1328533 + 363 WP_195701104.1 type II toxin-antitoxin system PemK/MazF family toxin -
IT773_RS06405 1328825..1329638 + 814 Protein_1247 EamA family transporter -
IT773_RS06410 1329695..1329958 - 264 WP_057814812.1 Txe/YoeB family addiction module toxin -
IT773_RS06415 1329948..1330229 - 282 WP_057814815.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
IT773_RS06420 1330655..1330897 + 243 WP_057814817.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1318188..1500688 182500


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(20-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(6-58)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10471.00 Da        Isoelectric Point: 9.7755

>T181668 WP_195701102.1 NZ_CP064761:1325684-1325947 [Companilactobacillus futsaii]
MSYSIKFKNSSKNDLKKIKNSPFCKKFDEIIKKLSVNPYDPSDNFEKLFPPEDKLYSRRLNIQHRIVYSIDEEKQIVHIY
SAWNHYA

Download         Length: 264 bp

>T181668 NZ_CP086061:c2271021-2270845 [Bacillus sp. BC1-43]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGATAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9867.98 Da        Isoelectric Point: 4.5895

>AT181668 WP_162256560.1 NZ_CP064761:1325418-1325681 [Companilactobacillus futsaii]
MQRMTNPTQARKDFYKIIKSVNENSTPIEINGRTEDDSAVIMSAKDYRSLQETLYLMNDGTLNKVHKAIADDSGETDITN
GVDWDKI

Download         Length: 264 bp

>AT181668 NZ_CP086061:2270962-2271062 [Bacillus sp. BC1-43]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACACAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References