Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 7765470..7766011 Replicon chromosome
Accession NZ_CP064703
Organism Bradyrhizobium sp. 170

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag IVB05_RS36240 Protein ID WP_247780867.1
Coordinates 7765745..7766011 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IVB05_RS36235 Protein ID WP_247780866.1
Coordinates 7765470..7765748 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB05_RS36210 (IVB05_36065) 7760476..7760994 - 519 WP_247780859.1 DUF992 domain-containing protein -
IVB05_RS36215 (IVB05_36070) 7761216..7762418 - 1203 WP_247780861.1 pyridoxal phosphate-dependent aminotransferase -
IVB05_RS36220 (IVB05_36075) 7763100..7763753 + 654 WP_247787261.1 glutathione S-transferase family protein -
IVB05_RS36225 (IVB05_36080) 7763960..7764133 + 174 WP_247780862.1 hypothetical protein -
IVB05_RS36230 (IVB05_36085) 7764203..7765363 + 1161 WP_247780864.1 PQQ-dependent sugar dehydrogenase -
IVB05_RS36235 (IVB05_36090) 7765470..7765748 + 279 WP_247780866.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IVB05_RS36240 (IVB05_36095) 7765745..7766011 + 267 WP_247780867.1 Txe/YoeB family addiction module toxin Toxin
IVB05_RS36245 (IVB05_36100) 7766111..7766464 - 354 WP_247780869.1 DMT family protein -
IVB05_RS36250 (IVB05_36105) 7766666..7767478 + 813 WP_247780871.1 PAS-domain containing protein -
IVB05_RS36255 (IVB05_36110) 7767772..7768233 + 462 WP_247780873.1 GNAT family N-acetyltransferase -
IVB05_RS36260 (IVB05_36115) 7768520..7769458 + 939 WP_247780874.1 aldo/keto reductase -
IVB05_RS36265 (IVB05_36120) 7769634..7770878 - 1245 WP_247780876.1 DUF1501 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10497.95 Da        Isoelectric Point: 8.8883

>T181653 WP_247780867.1 NZ_CP064703:7765745-7766011 [Bradyrhizobium sp. 170]
MKTAWTEDAWQDYLQWQKEDEKILEVINGLIKDIKRDPFKGLGKPEPLKHALQGWWSRRISGEHRLVYRVSGKGDTQQLD
IAQCRYHY

Download         Length: 267 bp

>T181653 NZ_CP086016:1314980-1315270 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
CTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCTCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCGACATTGAAAACCATGCTGGCA
GTAATGCGAGCTTTGGGCGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10380.83 Da        Isoelectric Point: 4.8893

>AT181653 WP_247780866.1 NZ_CP064703:7765470-7765748 [Bradyrhizobium sp. 170]
MAHVSYTELRNNLASYMDEVCDDRAPLFVTRQNARTVVLMAEDEYESLMETVHLLKSPANAVRLLRSIKEADEGKLTERE
LIEPTKAGSAKV

Download         Length: 279 bp

>AT181653 NZ_CP086016:1314684-1314983 [Pseudomonas aeruginosa]
ATGGTTGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCAAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATCCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References