Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_31
Location 8235210..8235829 Replicon chromosome
Accession NZ_CP064689
Organism Bradyrhizobium sp. 200

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag IVB30_RS38875 Protein ID WP_256474484.1
Coordinates 8235210..8235551 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IVB30_RS38880 Protein ID WP_247832354.1
Coordinates 8235548..8235829 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB30_RS38845 (IVB30_38465) 8231052..8232977 + 1926 WP_247838466.1 AsmA family protein -
IVB30_RS38850 (IVB30_38470) 8233058..8233366 - 309 WP_247832341.1 transcriptional regulator -
IVB30_RS38855 8233495..8233722 - 228 WP_247832343.1 hypothetical protein -
IVB30_RS38860 (IVB30_38475) 8233668..8233898 - 231 WP_247838595.1 hypothetical protein -
IVB30_RS38865 (IVB30_38480) 8233888..8234298 - 411 WP_247832345.1 hypothetical protein -
IVB30_RS38870 (IVB30_38485) 8234396..8234575 + 180 WP_247832351.1 DUF3072 domain-containing protein -
IVB30_RS38875 (IVB30_38490) 8235210..8235551 + 342 WP_256474484.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IVB30_RS38880 (IVB30_38495) 8235548..8235829 + 282 WP_247832354.1 helix-turn-helix transcriptional regulator Antitoxin
IVB30_RS38885 (IVB30_38500) 8236821..8238206 + 1386 WP_247832356.1 ABC transporter substrate-binding protein -
IVB30_RS38890 (IVB30_38505) 8238415..8239287 + 873 WP_247832359.1 sugar ABC transporter permease -
IVB30_RS38895 (IVB30_38510) 8239284..8240135 + 852 WP_247832365.1 carbohydrate ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(21-110)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-83)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12762.97 Da        Isoelectric Point: 10.9063

>T181634 WP_256474484.1 NZ_CP064689:8235210-8235551 [Bradyrhizobium sp. 200]
MRYKQACPWRVEILDETVAAEIAALPADMQARFLRLAERITSAGLESLSEPHVKHIGGKLWELRLTGRDGIARALYVTAI
GRRVVVVRAFVKKTQKTPRAEIELAQRRAKEIT

Download         Length: 342 bp

>T181634 NZ_CP085987:3500871-3501356 [Salmonella enterica]
GTGGGACGTGTAACAGCACCAGAACCTTTGTCCGCTTTTCATCAGGTAGCTGAGTTCGTCAGCGGTGAAGCTGTGCTCGA
TGACTGGTTGAAGCAAAAGGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACATTTGTGGTGTGCAAGAAAGACACGA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGTAGCGTCAACCATACAGAAGCGACAGGCAACCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATTATACTTGCCCGTCTTGCTGTCGATCTCTCATTCCATGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATCATGGTTCATGCACTTACCG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAATCATCACAAACTCAGCAGCGAACATTGTTCCTTAGGCTCCCT
CAATAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10157.78 Da        Isoelectric Point: 10.9619

>AT181634 WP_247832354.1 NZ_CP064689:8235548-8235829 [Bradyrhizobium sp. 200]
MTIQFDKLKARLLANPKVKAEYDALAPEFEIAAELLRARLRAGLSQAELAARMGTSQSTIARLENGQTLPSTKTLLRYAE
ATGSRVRVRLSAA

Download         Length: 282 bp

>AT181634 NZ_CP085987:3500596-3500883 [Salmonella enterica]
ATGCTATACAAGGGGTGTCTCATGAAATCAGATGTTCAACTTAACCTTAGAGCTAAGGAATCGCAGCGGGCGCTCATTGA
TGCAGCTGCGGAAATCCTTCACAAGTCACGTACAGATTTCATTCTGGAAACGGCCTGCCAGGCTGCCGAGAAAGTGATCC
TTGACCGCCGTGTATTTAACTTTAACGATGAGCAATATGAGGAGTTCATCAATCTGCTTGATGCACCGGTCGCAGATGAT
CCCGTTATCGAAAAACTGCTGGCAAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References