Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1620963..1621504 Replicon chromosome
Accession NZ_CP064689
Organism Bradyrhizobium sp. 200

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag IVB30_RS08005 Protein ID WP_247835233.1
Coordinates 1620963..1621229 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IVB30_RS08010 Protein ID WP_247835234.1
Coordinates 1621226..1621504 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB30_RS07980 (IVB30_07890) 1616094..1617032 - 939 WP_247835228.1 aldo/keto reductase -
IVB30_RS07985 (IVB30_07895) 1617531..1618892 + 1362 WP_247835229.1 amidohydrolase family protein -
IVB30_RS07990 (IVB30_07900) 1618926..1619387 - 462 WP_247835230.1 GNAT family N-acetyltransferase -
IVB30_RS07995 (IVB30_07905) 1619497..1620309 - 813 WP_247835231.1 PAS-domain containing protein -
IVB30_RS08000 (IVB30_07910) 1620511..1620864 + 354 WP_247835232.1 DMT family protein -
IVB30_RS08005 (IVB30_07915) 1620963..1621229 - 267 WP_247835233.1 Txe/YoeB family addiction module toxin Toxin
IVB30_RS08010 (IVB30_07920) 1621226..1621504 - 279 WP_247835234.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IVB30_RS08015 (IVB30_07925) 1621611..1622771 - 1161 WP_247835235.1 PQQ-dependent sugar dehydrogenase -
IVB30_RS08020 (IVB30_07930) 1622840..1623013 - 174 WP_247835236.1 hypothetical protein -
IVB30_RS08025 (IVB30_07935) 1623218..1623871 - 654 WP_247835237.1 glutathione S-transferase family protein -
IVB30_RS08030 (IVB30_07940) 1624542..1625744 + 1203 WP_247835238.1 pyridoxal phosphate-dependent aminotransferase -
IVB30_RS08035 (IVB30_07945) 1625878..1626393 + 516 WP_247835239.1 DUF992 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10511.98 Da        Isoelectric Point: 8.8884

>T181630 WP_247835233.1 NZ_CP064689:c1621229-1620963 [Bradyrhizobium sp. 200]
MKTAWTEDAWQEYLQWQKEDEKILEVINGLIKDIKRDPFKGLGKPEPLKHALQGWWSRRISGEHRLVYRVSGKGDTQQLD
IAQCRYHY

Download         Length: 267 bp

>T181630 NZ_CP085987:c2547901-2547617 [Salmonella enterica]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGAAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGGTCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGTCTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTTGCGGTCGGCAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10332.77 Da        Isoelectric Point: 5.1584

>AT181630 WP_247835234.1 NZ_CP064689:c1621504-1621226 [Bradyrhizobium sp. 200]
MAHVSYTELRNNLASYMDEVCDDRAPLFVTRQNARTVVLLAEDEYESLMATVHLLKSPANAVRLLRSIKEADEGRLTERE
LIEPTKAGSAKV

Download         Length: 279 bp

>AT181630 NZ_CP085987:c2548133-2547891 [Salmonella enterica]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCCGTGCGATTACTGTTCCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACTCTTAGCGACA
GTGAAGATGCATTGATTCAGACAGTTCGGGAGAGGCTGTCTAGTCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References