Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3693341..3693563 Replicon chromosome
Accession NZ_CP064678
Organism Escherichia coli K-12 strain CETR3G40

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag IVL03_RS17905 Protein ID WP_000141634.1
Coordinates 3693341..3693448 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3693497..3693563 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVL03_RS17880 3688594..3689346 - 753 Protein_3492 cellulose biosynthesis protein BcsQ -
IVL03_RS17885 3689358..3689546 - 189 WP_001063318.1 YhjR family protein -
IVL03_RS17890 3689819..3691390 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
IVL03_RS17895 3691387..3691578 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
IVL03_RS17900 3691575..3693254 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
IVL03_RS17905 3693341..3693448 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3693497..3693563 + 67 - - Antitoxin
IVL03_RS17910 3693924..3695195 + 1272 WP_001295225.1 transporter -
IVL03_RS17915 3695225..3696229 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
IVL03_RS17920 3696226..3697209 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
IVL03_RS17925 3697220..3698122 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T181445 WP_000141634.1 NZ_CP064678:c3693448-3693341 [Escherichia coli K-12]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T181445 NZ_CP085860:1975712-1975808 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 67 bp

>AT181445 NZ_CP064678:3693497-3693563 [Escherichia coli K-12]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References