Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3096892..3097727 Replicon chromosome
Accession NZ_CP064653
Organism Methylomonas sp. LL1

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag IVG45_RS14355 Protein ID WP_196434490.1
Coordinates 3097218..3097727 (+) Length 170 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag IVG45_RS14350 Protein ID WP_196434489.1
Coordinates 3096892..3097221 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVG45_RS14340 3093469..3095403 + 1935 WP_196434487.1 molecular chaperone HtpG -
IVG45_RS14345 3095546..3095977 + 432 WP_196434488.1 HEPN domain-containing protein -
IVG45_RS14350 3096892..3097221 + 330 WP_196434489.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
IVG45_RS14355 3097218..3097727 + 510 WP_196434490.1 type II toxin-antitoxin system YhaV family toxin Toxin
IVG45_RS14360 3097742..3097894 + 153 Protein_2729 CopG family transcriptional regulator -
IVG45_RS14365 3098062..3098361 - 300 WP_196434491.1 hypothetical protein -
IVG45_RS14370 3098548..3099060 + 513 WP_196434492.1 hypothetical protein -
IVG45_RS14375 3099127..3100236 + 1110 WP_196434493.1 tRNA guanosine(34) transglycosylase Tgt -
IVG45_RS14380 3100415..3100963 - 549 WP_196434494.1 hypothetical protein -
IVG45_RS14385 3101089..3101271 + 183 WP_196434495.1 hypothetical protein -
IVG45_RS14390 3101263..3101784 - 522 WP_196434496.1 YcxB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 19601.30 Da        Isoelectric Point: 9.5401

>T181271 WP_196434490.1 NZ_CP064653:3097218-3097727 [Methylomonas sp. LL1]
MSQPSSTFLVINGWSIFAHPLFLDQLDILIKQVEALREKAPAGYGRKNASKRLAAIAKLAFEIIPQDPARAEYRQGNTLG
EEHKHWFRAKFFQQYRLFFRYHAQSKIIVYAWVNDENTKRAYESDCDAYRVFRKMLESGHPPDDWNSLMPEAKAHSARLQ
SATEQAIQL

Download         Length: 510 bp

>T181271 NZ_CP085816:c3747962-3747471 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12171.68 Da        Isoelectric Point: 4.5378

>AT181271 WP_196434489.1 NZ_CP064653:3096892-3097221 [Methylomonas sp. LL1]
MPTTLEIESTLTDRYQTTVPETVRRALKLGKRDKIHYSILPDGAVLMSRATQSQEDDPVLGRFLGFLARDIANHPEHLQS
INTDLVTRLQSLTANIEVDLDAPLSADDE

Download         Length: 330 bp

>AT181271 NZ_CP085816:c3748252-3747959 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATTGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCTGCCCGTGCTGCCGCCGAGGAAGCGCTGA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References