Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) txpA-ratA/-
Location 694802..695068 Replicon chromosome
Accession NZ_CP064374
Organism Enterococcus faecalis strain PartL-Efaecalis-RM8376

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag IUJ47_RS03385 Protein ID WP_002411240.1
Coordinates 694802..694951 (+) Length 50 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 694884..695068 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUJ47_RS03365 689923..690138 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
IUJ47_RS03370 690277..691269 + 993 WP_002389493.1 biotin--[acetyl-CoA-carboxylase] ligase -
IUJ47_RS03375 691533..692171 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
IUJ47_RS03380 692857..694473 + 1617 WP_002389442.1 phosphatase PAP2/LCP family protein -
IUJ47_RS03385 694802..694951 + 150 WP_002411240.1 type I toxin-antitoxin system toxin PepG1 Toxin
- 694884..695068 - 185 - - Antitoxin
IUJ47_RS03390 695070..695210 + 141 WP_073340360.1 putative holin-like toxin -
IUJ47_RS03395 695441..695584 + 144 WP_002381035.1 putative holin-like toxin -
IUJ47_RS03400 695779..699606 - 3828 WP_010816211.1 WxL domain-containing protein -
IUJ47_RS03405 699593..699955 - 363 WP_002378868.1 LPXTG cell wall anchor domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(16-49)


Sequences


Toxin        


Download         Length: 50 a.a.        Molecular weight: 5738.05 Da        Isoelectric Point: 11.3858

>T180986 WP_002411240.1 NZ_CP064374:694802-694951 [Enterococcus faecalis]
MRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 150 bp

>T180986 NZ_CP085796:4161136-4161663 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTACTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 185 bp

>AT180986 NZ_CP064374:c695068-694884 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References