Detailed information of TA system TA180982

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 620857..621119
• Replicon: chromosome
• Accession: NZ_CP064374
• Organism: Enterococcus faecalis strain PartL-Efaecalis-RM8376

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: IUJ47_RS03045
• Protein ID: WP_002367458.1
• Coordinates: 620976..621119 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	620857..621043 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IUJ47_RS03030	616314..619058	+	2745	WP_025189146.1	glycosyl hydrolase family 65 protein	-
IUJ47_RS03035	619073..619723	+	651	WP_002389419.1	beta-phosphoglucomutase	-
IUJ47_RS03040	620143..620736	+	594	WP_002389391.1	PBECR4 domain-containing protein	-
-	620857..621043	+	187	-	-	Antitoxin
IUJ47_RS03045	620976..621119	-	144	WP_002367458.1	type I toxin-antitoxin system toxin PepG1	Toxin
IUJ47_RS03050	621351..622322	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
IUJ47_RS03055	622497..622934	-	438	WP_002389480.1	peptide-methionine (R)-S-oxide reductase MsrB	-
IUJ47_RS03060	623067..623621	-	555	WP_002354869.1	Maf family protein	-
IUJ47_RS03065	623646..625778	-	2133	WP_002389406.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5311.50 Da
• Isoelectric Point: 10.8331

>T180982 WP_002367458.1 NZ_CP064374:c621119-620976 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

>T180982 NZ_CP085796:c1548279-1548022 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCAAAACCCACATGACCACCTATTACTCACAAATCCCCAGCCT
GCATCTTAAGGGCGACTGGCTGGAAGAAGCGGGATTTAAGACCGGGCGCGGCGTCACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAGCAGCTTTATCAGGCTAAACAGGTGGTTAAGGGAATT
AAGGACGTGCTGGTTTAG

Antitoxin

Nucleotide

• Length: 187 bp

>AT180982 NZ_CP064374:620857-621043 [Enterococcus faecalis]
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin