Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 549782..550007 | Replicon | chromosome |
Accession | NZ_CP064374 | ||
Organism | Enterococcus faecalis strain PartL-Efaecalis-RM8376 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | IUJ47_RS02715 | Protein ID | WP_075551663.1 |
Coordinates | 549906..550007 (-) | Length | 34 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 549782..549961 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IUJ47_RS02685 | 545001..545954 | - | 954 | WP_002370087.1 | siderophore ABC transporter substrate-binding protein | - |
IUJ47_RS02690 | 545993..546748 | - | 756 | WP_002354962.1 | ATP-binding cassette domain-containing protein | - |
IUJ47_RS02695 | 546745..547710 | - | 966 | WP_002371665.1 | iron chelate uptake ABC transporter family permease subunit | - |
IUJ47_RS02700 | 547707..548654 | - | 948 | WP_002354960.1 | iron chelate uptake ABC transporter family permease subunit | - |
IUJ47_RS02705 | 548839..549291 | + | 453 | WP_002389410.1 | YueI family protein | - |
IUJ47_RS02710 | 549473..549574 | - | 102 | WP_021164441.1 | putative holin-like toxin | - |
- | 549782..549961 | + | 180 | - | - | Antitoxin |
IUJ47_RS02715 | 549906..550007 | - | 102 | WP_075551663.1 | putative holin-like toxin | Toxin |
IUJ47_RS02720 | 550197..552467 | - | 2271 | WP_002389492.1 | bifunctional glutamate--cysteine ligase/glutathione synthetase | - |
IUJ47_RS02725 | 552638..553138 | + | 501 | WP_002372831.1 | cysteine hydrolase family protein | - |
IUJ47_RS02730 | 553537..554433 | + | 897 | WP_002389477.1 | YitT family protein | - |
IUJ47_RS02735 | 554484..554882 | - | 399 | WP_002354951.1 | glyoxalase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 34 a.a. Molecular weight: 3599.34 Da Isoelectric Point: 4.5869
>T180981 WP_075551663.1 NZ_CP064374:c550007-549906 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK
MSIEAALELMISFAAFVALLIFGILEATKNDKK
Download Length: 102 bp
>T180981 NZ_CP085796:1163073-1163360 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA
Antitoxin
Download Length: 180 bp
>AT180981 NZ_CP064374:549782-549961 [Enterococcus faecalis]
TGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGT
TTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACC
GAAAATCAGTAGTGCAACAA
TGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGT
TTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACC
GAAAATCAGTAGTGCAACAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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