180971

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) txpA-ratA/-
Location 549317..549574 Replicon chromosome
Accession NZ_CP064374
Organism Enterococcus faecalis strain PartL-Efaecalis-RM8376

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag IUJ47_RS02710 Protein ID WP_021164441.1
Coordinates 549473..549574 (-) Length 34 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 549317..549524 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUJ47_RS02685 545001..545954 - 954 WP_002370087.1 siderophore ABC transporter substrate-binding protein -
IUJ47_RS02690 545993..546748 - 756 WP_002354962.1 ATP-binding cassette domain-containing protein -
IUJ47_RS02695 546745..547710 - 966 WP_002371665.1 iron chelate uptake ABC transporter family permease subunit -
IUJ47_RS02700 547707..548654 - 948 WP_002354960.1 iron chelate uptake ABC transporter family permease subunit -
IUJ47_RS02705 548839..549291 + 453 WP_002389410.1 YueI family protein -
- 549317..549524 + 208 - - Antitoxin
IUJ47_RS02710 549473..549574 - 102 WP_021164441.1 putative holin-like toxin Toxin
IUJ47_RS02715 549906..550007 - 102 WP_075551663.1 putative holin-like toxin -
IUJ47_RS02720 550197..552467 - 2271 WP_002389492.1 bifunctional glutamate--cysteine ligase/glutathione synthetase -
IUJ47_RS02725 552638..553138 + 501 WP_002372831.1 cysteine hydrolase family protein -
IUJ47_RS02730 553537..554433 + 897 WP_002389477.1 YitT family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-33)


Sequences


Toxin        


Download         Length: 34 a.a.        Molecular weight: 3598.36 Da        Isoelectric Point: 6.0656

>T180971 WP_021164441.1 NZ_CP064374:c549574-549473 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNNKK

Download         Length: 102 bp

>T180971 NZ_CP085795:3157461-3157564 [Salmonella enterica subsp. enterica serovar Enteritidis]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 208 bp

>AT180971 NZ_CP064374:549317-549524 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATAAAGATGAAAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAAC
ACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTGAATCTTAACCGTTCGGCCTACGAAGCTTGTGAACGGTTAT
TTTTTATTGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References