Detailed information of TA system TA180945

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1941203..1941385
• Replicon: chromosome
• Accession: NZ_CP064365
• Organism: Staphylococcus aureus strain PartF-Saureus-RM8376

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IUJ41_RS09830
• Protein ID: WP_001801861.1
• Coordinates: 1941290..1941385 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1941203..1941262 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IUJ41_RS09815 (IUJ41_09785)	1940341..1940718	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
IUJ41_RS09820 (IUJ41_09790)	1940912..1941088	+	177	Protein_1887	transposase	-
IUJ41_RS09825 (IUJ41_09795)	1941066..1941167	-	102	WP_001791893.1	hypothetical protein	-
-	1941203..1941262	+	60	-	-	Antitoxin
IUJ41_RS09830 (IUJ41_09800)	1941290..1941385	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IUJ41_RS09835 (IUJ41_09805)	1941588..1941731	+	144	WP_001549059.1	transposase	-
IUJ41_RS09840 (IUJ41_09810)	1942335..1942718	+	384	WP_000070812.1	hypothetical protein	-
IUJ41_RS09845 (IUJ41_09815)	1942729..1942905	+	177	WP_000375476.1	hypothetical protein	-
IUJ41_RS09850 (IUJ41_09820)	1942907..1943092	+	186	WP_000809857.1	hypothetical protein	-
IUJ41_RS09855 (IUJ41_09825)	1943206..1943847	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
IUJ41_RS09860 (IUJ41_09830)	1944065..1944616	-	552	WP_000414205.1	hypothetical protein	-
IUJ41_RS09865 (IUJ41_09835)	1944714..1945058	-	345	WP_000627551.1	DUF3969 family protein	-
IUJ41_RS09870 (IUJ41_09840)	1945099..1945725	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1922684..1978826	56142

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T180945 WP_001801861.1 NZ_CP064365:c1941385-1941290 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T180945 NZ_CP085794:c860463-860095 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTACCGGGTACTCAATCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCGCTATATCCCGTGGGCATATCTTCAATGATGGTAACAAACGTACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAGCAAATTGTCGTTCGCTTACGCGCCTGA

Antitoxin

Nucleotide

• Length: 60 bp

>AT180945 NZ_CP064365:1941203-1941262 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin