Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
| Location | 457996..458702 | Replicon | chromosome |
| Accession | NZ_CP064330 | ||
| Organism | Xylella fastidiosa subsp. fastidiosa strain Bakersfield-13 | ||
Toxin (Protein)
| Gene name | mqsR | Uniprot ID | Q87EE2 |
| Locus tag | IUD22_RS01885 | Protein ID | WP_004090696.1 |
| Coordinates | 457996..458298 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | mqsA | Uniprot ID | Q87EE1 |
| Locus tag | IUD22_RS01890 | Protein ID | WP_004090697.1 |
| Coordinates | 458301..458702 (+) | Length | 134 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IUD22_RS01850 | 453764..454483 | - | 720 | Protein_346 | phage late control D family protein | - |
| IUD22_RS01855 | 454383..455354 | - | 972 | WP_011097609.1 | hypothetical protein | - |
| IUD22_RS01860 | 455362..455919 | - | 558 | WP_011097610.1 | phage tail protein I | - |
| IUD22_RS01865 | 455912..456805 | - | 894 | WP_011097611.1 | baseplate J/gp47 family protein | - |
| IUD22_RS01870 | 456805..457143 | - | 339 | WP_004090694.1 | GPW/gp25 family protein | - |
| IUD22_RS01875 | 457341..457622 | + | 282 | WP_004090695.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| IUD22_RS01880 | 457633..457908 | + | 276 | WP_004085172.1 | HigA family addiction module antidote protein | - |
| IUD22_RS01885 | 457996..458298 | + | 303 | WP_004090696.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
| IUD22_RS01890 | 458301..458702 | + | 402 | WP_004090697.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
| IUD22_RS01895 | 458771..459358 | - | 588 | WP_011097612.1 | phage baseplate assembly protein V | - |
| IUD22_RS01900 | 459355..459897 | - | 543 | WP_011097613.1 | hypothetical protein | - |
| IUD22_RS01905 | 459873..460394 | - | 522 | WP_011097614.1 | hypothetical protein | - |
| IUD22_RS01910 | 460391..460714 | - | 324 | WP_011097935.1 | hypothetical protein | - |
| IUD22_RS01915 | 460714..460974 | - | 261 | WP_011097616.1 | hypothetical protein | - |
| IUD22_RS01920 | 460992..462866 | - | 1875 | WP_011097617.1 | phage major capsid protein | - |
| IUD22_RS01925 | 462863..463495 | - | 633 | WP_194957365.1 | phage portal protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 445939..468772 | 22833 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 10948.71 Da Isoelectric Point: 8.0251
>T180835 WP_004090696.1 NZ_CP064330:457996-458298 [Xylella fastidiosa subsp. fastidiosa]
MEKGTSHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
MEKGTSHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
Download Length: 303 bp
>T180835 NZ_CP085748:3684787-3685260 [Enterobacter hormaechei]
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTAGCTTCACTGGAAATTCTGGTGCACGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTGATATCCCGGATGACCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCCGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
ACAAAGCACTCAATTCTGTTGAATTAATGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTAGCTTCACTGGAAATTCTGGTGCACGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTGATATCCCGGATGACCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCCGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
ACAAAGCACTCAATTCTGTTGAATTAATGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14944.02 Da Isoelectric Point: 7.1650
>AT180835 WP_004090697.1 NZ_CP064330:458301-458702 [Xylella fastidiosa subsp. fastidiosa]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSS
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSS
Download Length: 402 bp
>AT180835 NZ_CP085748:3684347-3684790 [Enterobacter hormaechei]
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTGCCTGCAAGCAGAGGCAT
GCGGCTGATAGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATCAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTTGATGCGGCTGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATCGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTGCCTGCAAGCAGAGGCAT
GCGGCTGATAGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATCAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTTGATGCGGCTGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATCGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|