Detailed information of TA system TA180117

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 1569202..1569448
• Replicon: chromosome
• Accession: NZ_CP064096
• Organism: Bacillus subtilis strain N1142-3at

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: IRJ28_RS08760
• Protein ID: WP_109789044.1
• Coordinates: 1569356..1569448 (-)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	1569202..1569375 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IRJ28_RS08740	1565116..1565673	+	558	WP_004399321.1	SMI1/KNR4 family protein	-
IRJ28_RS08745	1565775..1567577	+	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
IRJ28_RS08750	1567587..1568045	+	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
IRJ28_RS08755	1568245..1569087	+	843	WP_003231327.1	hypothetical protein	-
-	1569202..1569375	+	174	-	-	Antitoxin
IRJ28_RS08760	1569356..1569448	-	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
IRJ28_RS08765	1569737..1570069	+	333	WP_026009814.1	hypothetical protein	-
IRJ28_RS08770	1570302..1573907	+	3606	WP_004399367.1	P-loop NTPase fold protein	-
IRJ28_RS08775	1573954..1574289	-	336	WP_009967409.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1522661..1635930	113269

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T180117 WP_109789044.1 NZ_CP064096:c1569448-1569356 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T180117 NZ_CP085069:754939-755235 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin

Nucleotide

• Length: 174 bp

>AT180117 NZ_CP064096:1569202-1569375 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin