Detailed information of TA system TA180096

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 4104838..4105084
• Replicon: chromosome
• Accession: NZ_CP064095
• Organism: Bacillus subtilis strain N1303-2Ay

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: IRJ27_RS21710
• Protein ID: WP_109789044.1
• Coordinates: 4104992..4105084 (-)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	4104838..4105011 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IRJ27_RS21690	4100752..4101309	+	558	WP_004399321.1	SMI1/KNR4 family protein	-
IRJ27_RS21695	4101411..4103213	+	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
IRJ27_RS21700	4103223..4103681	+	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
IRJ27_RS21705	4103881..4104723	+	843	WP_003231327.1	hypothetical protein	-
-	4104838..4105011	+	174	-	-	Antitoxin
IRJ27_RS21710	4104992..4105084	-	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
IRJ27_RS21715	4105373..4105705	+	333	WP_026009814.1	hypothetical protein	-
IRJ27_RS21720	4105938..4109543	+	3606	WP_004399367.1	P-loop NTPase fold protein	-
IRJ27_RS21725	4109590..4109925	-	336	WP_009967409.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	4095421..4118689	23268

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T180096 WP_109789044.1 NZ_CP064095:c4105084-4104992 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T180096 NZ_CP085063:c2809768-2809595 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Nucleotide

• Length: 174 bp

>AT180096 NZ_CP064095:4104838-4105011 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin