Detailed information of TA system TA180073

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 3615981..3616227
• Replicon: chromosome
• Accession: NZ_CP064094
• Organism: Bacillus subtilis strain N1108-5at

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: IRJ26_RS19520
• Protein ID: WP_109789044.1
• Coordinates: 3616135..3616227 (-)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	3615981..3616154 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IRJ26_RS19500	3611895..3612452	+	558	WP_004399321.1	SMI1/KNR4 family protein	-
IRJ26_RS19505	3612554..3614356	+	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
IRJ26_RS19510	3614366..3614824	+	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
IRJ26_RS19515	3615024..3615866	+	843	WP_003231327.1	hypothetical protein	-
-	3615981..3616154	+	174	-	-	Antitoxin
IRJ26_RS19520	3616135..3616227	-	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
IRJ26_RS19525	3616516..3616848	+	333	WP_026009814.1	hypothetical protein	-
IRJ26_RS19530	3617081..3620686	+	3606	WP_004399367.1	P-loop NTPase fold protein	-
IRJ26_RS19535	3620733..3621068	-	336	WP_009967409.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3606564..3630242	23678

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T180073 WP_109789044.1 NZ_CP064094:c3616227-3616135 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T180073 NZ_CP085060:c3917112-3916816 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin

Nucleotide

• Length: 174 bp

>AT180073 NZ_CP064094:3615981-3616154 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin