Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 181153..181347 Replicon chromosome
Accession NZ_CP063980
Organism Enterococcus faecalis strain AR_0780

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag ISN59_RS00860 Protein ID WP_015543884.1
Coordinates 181153..181248 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 181283..181347 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN59_RS00840 (176330) 176330..177445 + 1116 WP_010709201.1 FAD-dependent oxidoreductase -
ISN59_RS00845 (177514) 177514..178668 - 1155 WP_010709200.1 mannitol-1-phosphate 5-dehydrogenase -
ISN59_RS00850 (178683) 178683..179120 - 438 WP_002355279.1 PTS sugar transporter subunit IIA -
ISN59_RS00855 (179135) 179135..180907 - 1773 WP_113843943.1 PTS mannitol-specific transporter subunit IIBC -
ISN59_RS00860 (181153) 181153..181248 + 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
- (181283) 181283..181347 - 65 NuclAT_9 - Antitoxin
ISN59_RS00865 (181503) 181503..181937 - 435 WP_002358391.1 PTS sugar transporter subunit IIA -
ISN59_RS00870 (181948) 181948..183981 - 2034 WP_002361171.1 PRD domain-containing protein -
ISN59_RS00875 (183972) 183972..185714 - 1743 WP_162780888.1 PTS transporter subunit EIIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T179863 WP_015543884.1 NZ_CP063980:181153-181248 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T179863 NZ_CP084897:c1270551-1270444 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 65 bp

>AT179863 NZ_CP063980:c181347-181283 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References