Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1300334..1301006 Replicon chromosome
Accession NZ_CP063773
Organism Pectobacterium carotovorum subsp. carotovorum PCCS1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag IQ281_RS05920 Protein ID WP_180779426.1
Coordinates 1300334..1300720 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IQ281_RS05925 Protein ID WP_180779427.1
Coordinates 1300707..1301006 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IQ281_RS05895 1296247..1297389 + 1143 WP_194431340.1 FMNH2-dependent alkanesulfonate monooxygenase -
IQ281_RS05900 1297400..1298194 + 795 WP_180779424.1 aliphatic sulfonate ABC transporter permease SsuC -
IQ281_RS05905 1298191..1298991 + 801 WP_194431341.1 aliphatic sulfonates ABC transporter ATP-binding protein -
IQ281_RS05910 1299164..1299421 + 258 WP_012772768.1 DUF1471 domain-containing protein -
IQ281_RS05915 1299621..1300118 - 498 WP_180779425.1 GNAT family N-acetyltransferase -
IQ281_RS05920 1300334..1300720 + 387 WP_180779426.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IQ281_RS05925 1300707..1301006 + 300 WP_180779427.1 XRE family transcriptional regulator Antitoxin
IQ281_RS05930 1301043..1302842 - 1800 WP_194431342.1 ABC transporter ATP-binding protein -
IQ281_RS05935 1302882..1303790 - 909 WP_012772766.1 ABC transporter permease -
IQ281_RS05940 1303787..1304764 - 978 WP_012772765.1 ABC transporter permease -
IQ281_RS05945 1304764..1305771 - 1008 WP_194431343.1 nucleoside hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-113)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-80)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14834.84 Da        Isoelectric Point: 4.7331

>T178773 WP_180779426.1 NZ_CP063773:1300334-1300720 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MEVYRLAWEIVTRALFDTWFDEQTETVQEEVLAHLGILEEDGPQLGRPQVDQIKGSQYKNMKELRVQVGGHPFRTFFAFD
RTRKAIVLCAGDKKGENEKLFYERMIKIADAEFTSHLISPEVKEDGDI

Download         Length: 387 bp

>T178773 NZ_CP084284:c1028161-1027796 [Caballeronia zhejiangensis]
ATGGTAAGAGCGCTTTTCGACACGAACATCCTGATCGATTACCTGTTGGGAATCGATGCGGCACGCAAGGAGATCGAGCG
TTACGAAGAGCGGTCGATCAGCATCATCACGCTCATGGAAGTTCTAGAGGGCGCCAAACCCGACAGTGAAGCGTCGCTGC
GCGCCTGGCTGTCCACCTTCGATCTCGTGCCGCTCGATTCGGCCGTCGCGAACCTCGCAATCGGAATTCGCAGGAAATCG
CGCATCAAGTTGCCGGATGCGATCGTGTGGGCGTCGGCGCAATCGGTGAATGCGCTGCTCGTTTCGCGCAACTCGAAGGA
CTTCCCGCCCGACGATCCGGGCGTGCGGATGCCCTATCAACTGTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11082.10 Da        Isoelectric Point: 10.6442

>AT178773 WP_180779427.1 NZ_CP063773:1300707-1301006 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MATFKEMMAKRSPESRARIEARTAEIRQEITLAKLREELNMSQTQLALALGVKQPSIVKMEKVENDPKLSTLKRYVTALG
GKLTLDVTLPDGKRIALTL

Download         Length: 300 bp

>AT178773 NZ_CP084284:c1028373-1028155 [Caballeronia zhejiangensis]
ATGGGAAGGATCTTGATCGATTTGCCCGACGAACAGATAGACGAACTCGCCGCGATCGGCGAAGAGCAGCAGCGCCCGCG
AGCCGCGGTCATTCGGGACGCGATCAGCGCGTACGTCGCGAGCAACAAGCGCCGTTCTGCCGTCGATGTGTTCGGCTTAT
GGCAAGAGCGAAAGATCGATGGATTGCAGTATCAGCGGGAGCTGCGCGAAGAATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References