Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | symER/SymE(toxin) |
Location | 1363142..1363554 | Replicon | chromosome |
Accession | NZ_CP063492 | ||
Organism | Escherichia coli strain EF5-18-41 |
Toxin (Protein)
Gene name | symE | Uniprot ID | U9YSY7 |
Locus tag | IQS14_RS06490 | Protein ID | WP_000132601.1 |
Coordinates | 1363142..1363483 (-) | Length | 114 a.a. |
Antitoxin (RNA)
Gene name | symR | ||
Locus tag | - | ||
Coordinates | 1363478..1363554 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IQS14_RS06480 | 1360555..1361601 | - | 1047 | WP_000437621.1 | 5-methylcytosine-specific restriction endonuclease system specificity protein McrC | - |
IQS14_RS06485 | 1361601..1362980 | - | 1380 | WP_000443951.1 | 5-methylcytosine-specific restriction endonuclease subunit McrB | - |
IQS14_RS06490 | 1363142..1363483 | - | 342 | WP_000132601.1 | endoribonuclease SymE | Toxin |
- | 1363478..1363554 | + | 77 | NuclAT_12 | - | Antitoxin |
- | 1363478..1363554 | + | 77 | NuclAT_12 | - | Antitoxin |
- | 1363478..1363554 | + | 77 | NuclAT_12 | - | Antitoxin |
- | 1363478..1363554 | + | 77 | NuclAT_12 | - | Antitoxin |
- | 1363478..1363554 | + | 77 | NuclAT_13 | - | Antitoxin |
- | 1363478..1363554 | + | 77 | NuclAT_13 | - | Antitoxin |
- | 1363478..1363554 | + | 77 | NuclAT_13 | - | Antitoxin |
- | 1363478..1363554 | + | 77 | NuclAT_13 | - | Antitoxin |
IQS14_RS06495 | 1363711..1365105 | - | 1395 | WP_001272445.1 | type I restriction-modification system specificity subunit | - |
IQS14_RS06500 | 1365102..1366691 | - | 1590 | WP_001063200.1 | type I restriction-modification system methyltransferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 1350851..1365105 | 14254 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12203.02 Da Isoelectric Point: 8.5012
>T178472 WP_000132601.1 NZ_CP063492:c1363483-1363142 [Escherichia coli]
MTDTHSIAQPFEAEVSPANNRHVTVGYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVQAFIGVIAGKQKVA
MTDTHSIAQPFEAEVSPANNRHVTVGYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVQAFIGVIAGKQKVA
Download Length: 342 bp
>T178472 NZ_CP084032:c30241-29855 [Pectobacterium colocasium]
ATGGAGGTTTACAGATTGGCATGGGAAATAGTCACACGGGCACTATTCGATACGTGGTTTGATGAGCAAACCGAAACGGT
ACAGGAAGAGGTTTTGGCACACCTCGGTATACTCGAAGAAGATGGCCCACAGCTAGGGCGACCACAGGTTGATCAGATTA
AAGGCTCACAATACAAAAATATGAAGGAGCTTCGAGTTCAGGTTGGCGGCCACCCATTCCGAACATTCTTCGCGTTTGAT
CGGACACGTAAAGCGATTGTTTTATGTGCGGGAGATAAGAAAGGCGAAAATGAAAAATTGTTCTACGAACGTATGATTAA
GATCGCAGACGCTGAGTTTACATCGCATCTGATATCACCGGAGGTAAAAGAAGATGGCGACATTTAA
ATGGAGGTTTACAGATTGGCATGGGAAATAGTCACACGGGCACTATTCGATACGTGGTTTGATGAGCAAACCGAAACGGT
ACAGGAAGAGGTTTTGGCACACCTCGGTATACTCGAAGAAGATGGCCCACAGCTAGGGCGACCACAGGTTGATCAGATTA
AAGGCTCACAATACAAAAATATGAAGGAGCTTCGAGTTCAGGTTGGCGGCCACCCATTCCGAACATTCTTCGCGTTTGAT
CGGACACGTAAAGCGATTGTTTTATGTGCGGGAGATAAGAAAGGCGAAAATGAAAAATTGTTCTACGAACGTATGATTAA
GATCGCAGACGCTGAGTTTACATCGCATCTGATATCACCGGAGGTAAAAGAAGATGGCGACATTTAA
Antitoxin
Download Length: 77 bp
>AT178472 NZ_CP063492:1363478-1363554 [Escherichia coli]
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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