Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 363693..365044 Replicon chromosome
Accession NZ_CP063380
Organism Pectobacterium versatile strain ECC15

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag IMY97_RS01655 Protein ID WP_188246875.1
Coordinates 363693..364733 (-) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag IMY97_RS01660 Protein ID WP_103943147.1
Coordinates 364730..365044 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMY97_RS01625 (IMY97_22425) 358855..360099 - 1245 WP_242934915.1 AAA domain-containing protein -
IMY97_RS01630 (IMY97_01570) 360254..360541 - 288 WP_116186077.1 type II toxin-antitoxin system RelE/ParE family toxin -
IMY97_RS01635 (IMY97_01575) 360538..360789 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
IMY97_RS01640 (IMY97_01580) 361047..361952 + 906 WP_188246876.1 siderophore-interacting protein -
IMY97_RS01645 (IMY97_01585) 361987..362742 - 756 WP_130623730.1 thiol:disulfide interchange protein DsbG -
IMY97_RS01650 (IMY97_01590) 363009..363632 + 624 WP_119159034.1 LysE family translocator -
IMY97_RS01655 (IMY97_01595) 363693..364733 - 1041 WP_188246875.1 HipA domain-containing protein Toxin
IMY97_RS01660 (IMY97_01600) 364730..365044 - 315 WP_103943147.1 HipA N-terminal domain-containing protein Antitoxin
IMY97_RS01665 (IMY97_01605) 365029..365355 - 327 WP_103862833.1 helix-turn-helix domain-containing protein -
IMY97_RS01670 (IMY97_01610) 365514..366386 - 873 WP_103862832.1 LysR family transcriptional regulator -
IMY97_RS01675 (IMY97_01615) 366489..366998 + 510 WP_039542420.1 phenolic acid decarboxylase -
IMY97_RS01680 (IMY97_01620) 367055..368188 - 1134 WP_103971661.1 alkylhydroperoxidase domain protein -
IMY97_RS01685 (IMY97_01625) 368185..369219 - 1035 WP_103862830.1 putative FMN-dependent luciferase-like monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - rfaD 337966..510621 172655


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39551.49 Da        Isoelectric Point: 6.2690

>T178062 WP_188246875.1 NZ_CP063380:c364733-363693 [Pectobacterium versatile]
MTTCRILLTPLTHEEEMATGYSRKGLKHLAGSIHASPDLRFTRQQFMHDLPQTQKGMSISGYQPKIQMVLEERAFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPDQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIRADGRQYVSYERLALFLSEHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGQLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSEKLTKKLLADFIKEAECVESTYRDSFMP
AEAIDTTLRCYRHRLNLMSILDAERI

Download         Length: 1041 bp

>T178062 NZ_CP083831:c319584-319297 [Enterobacter asburiae]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11840.54 Da        Isoelectric Point: 7.1966

>AT178062 WP_103943147.1 NZ_CP063380:c365044-364730 [Pectobacterium versatile]
VRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFRSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDEA

Download         Length: 315 bp

>AT178062 NZ_CP083831:c319823-319584 [Enterobacter asburiae]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References