Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 736427..737082 Replicon chromosome
Accession NZ_CP063358
Organism Pseudomonas stutzeri strain ZDHY95

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag IM687_RS03425 Protein ID WP_196111973.1
Coordinates 736738..737082 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IM687_RS03420 Protein ID WP_027600721.1
Coordinates 736427..736741 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IM687_RS03390 732744..732983 - 240 WP_196111968.1 entry exclusion lipoprotein TrbK -
IM687_RS03395 732994..733773 - 780 WP_196111969.1 P-type conjugative transfer protein TrbJ -
IM687_RS03400 733754..734149 - 396 WP_196111970.1 conjugal transfer transcriptional regulator TraJ -
IM687_RS03405 734423..734815 - 393 WP_196111971.1 TraK family protein -
IM687_RS03410 734833..735687 - 855 WP_196111972.1 helix-turn-helix domain-containing protein -
IM687_RS03415 735687..735914 - 228 WP_071579492.1 helix-turn-helix domain-containing protein -
IM687_RS03420 736427..736741 - 315 WP_027600721.1 transcriptional regulator Antitoxin
IM687_RS03425 736738..737082 - 345 WP_196111973.1 toxin Toxin
IM687_RS03430 737130..738203 - 1074 WP_196111974.1 site-specific integrase -
IM687_RS03440 738519..740372 - 1854 WP_014595737.1 RNA polymerase sigma factor RpoD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 734833..753418 18585


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13417.41 Da        Isoelectric Point: 9.9930

>T178009 WP_196111973.1 NZ_CP063358:c737082-736738 [Pseudomonas stutzeri]
MKALFVELPPFERHRADYLDDEAFRSFQRLLMKNPEAGDVIQGTGGLRKIRFADERRQKGKRGGIRVIYYWWLGGAQFWL
FTLYGKDVQDDLNEQQKKLLKQLLQAEIDARTTP

Download         Length: 345 bp

>T178009 NZ_CP083809:2416398-2416709 [Pantoea agglomerans]
ATGCACGTCATTTCAAAAGAGCCATTTGAGCAAGCGGCGCGGTTATTTCCTAACGATGCCAGGGCCATCAAGGCGCTGTA
TCGTCTGGTACGCGAAACAGACTTCAAAACGCCCGAAGAACTGCGCGCTGCCGTACCGAGCCTGGACCATTTTAAATACC
GTGACAAATGGTGGGTTTTAGATGTAGGGGGCAACAATTTGCGAGTAATCGCCTACATAAACTTCGTGAATAAGCGCTTC
TACGTTAAGCACATCGCTACCCACGCTGAATACGATAAGCTGACTCGCTACTATCGGGAGAATAAAGAATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12021.81 Da        Isoelectric Point: 6.4735

>AT178009 WP_027600721.1 NZ_CP063358:c736741-736427 [Pseudomonas stutzeri]
MKRDIFAELVEGFEALEDERQGKVTLRSHKVQLPELCEVSSEELVEIRQKLNMSRPVFAMYLRTNPRTLENWEQGRAKPN
AQATTLIRLVQKYPETVEHLAALG

Download         Length: 315 bp

>AT178009 NZ_CP083809:2416706-2417125 [Pantoea agglomerans]
ATGATCGCCGACACCATTAAAGCTATCGAAGCGACCAAACAACTGGTCGCGGCTGTTCCCCTGCTGGGGGGCAGCAACTC
AGAGAAAGACTACCGTGACGCACTGGCTCTAGTGGACTACCTGATTGACCACGACGATGAAAACCCGCTGATCGACTTTC
TTGCGGCAAAAATTGCACACTACGAGGACAATAGCGAGCGCTTTGCAGAGTTCAACAAAGAGGTTGACGAAATGCCAGTT
GGCGTTGCGCTGCTGCGCACGTTGATTGACCAGCATAGATTGTCTTACTCCGACCTGAGCGAGGAAATCGGCTCTAAATC
GCTTGTTAGCCAAATCCTGTCCGGTCAGCGCTCTCTGACGATCTCACATATCAAGGCTCTTTCCGCTCGCTTCGGGGTAA
AACCTCAATGGTTCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References