Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 1102293..1102987 Replicon chromosome
Accession NZ_CP063242
Organism Pectobacterium carotovorum strain XP-13

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag IHJ55_RS04900 Protein ID WP_203471241.1
Coordinates 1102589..1102987 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag IHJ55_RS04895 Protein ID WP_203470865.1
Coordinates 1102293..1102586 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHJ55_RS04865 1097504..1097740 + 237 WP_203470861.1 hypothetical protein -
IHJ55_RS04870 1097873..1098373 + 501 WP_203471240.1 pilus assembly protein PilS -
IHJ55_RS04875 1098512..1100104 + 1593 WP_203470862.1 shufflon system plasmid conjugative transfer pilus tip adhesin PilV -
IHJ55_RS04880 1100199..1100408 + 210 WP_203470863.1 hypothetical protein -
IHJ55_RS04885 1100620..1100799 - 180 WP_180788260.1 hypothetical protein -
IHJ55_RS04890 1101165..1101995 - 831 WP_203470864.1 hypothetical protein -
IHJ55_RS04895 1102293..1102586 + 294 WP_203470865.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
IHJ55_RS04900 1102589..1102987 + 399 WP_203471241.1 type II toxin-antitoxin system YafO family toxin Toxin
IHJ55_RS04905 1103406..1103660 + 255 WP_203470866.1 DNA polymerase III subunit theta -
IHJ55_RS04910 1103912..1104460 + 549 WP_203470867.1 hypothetical protein -
IHJ55_RS04915 1104760..1105704 - 945 WP_203470868.1 LysR family transcriptional regulator -
IHJ55_RS04920 1106362..1106850 + 489 WP_203471242.1 isochorismatase family protein -
IHJ55_RS04925 1106977..1107975 + 999 WP_203470869.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1072968..1103148 30180


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15268.54 Da        Isoelectric Point: 7.1284

>T177829 WP_203471241.1 NZ_CP063242:1102589-1102987 [Pectobacterium carotovorum]
IRIFKSALIRQQLSQQELDDLAADFLSYKKDGVLPDTFGRDAPYDDDRTYPLVKEEQVAHIHLADADAPFPKFLRQFKRT
SDQAHLVYCQGAMDPDAYLLIIILKPEAHKMARNNNHMHKIGMMAEAFRMKH

Download         Length: 399 bp

>T177829 NZ_CP083709:c454673-454570 [Enterobacter cloacae complex sp. ECL352]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10965.41 Da        Isoelectric Point: 4.9059

>AT177829 WP_203470865.1 NZ_CP063242:1102293-1102586 [Pectobacterium carotovorum]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEEKQGRVHTAARFRPSADRLSDIADSG
QKLLQNASDKDLTEFTE

Download         Length: 294 bp

>AT177829 NZ_CP083709:454564-454708 [Enterobacter cloacae complex sp. ECL352]
ACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References