Detailed information of TA system TA177627

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-as-bsrE/-
• Location: 2204427..2204644
• Replicon: chromosome
• Accession: NZ_CP063150
• Organism: Bacillus subtilis strain s-16

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: IMY14_RS11280
• Protein ID: WP_019712271.1
• Coordinates: 2204427..2204603 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2204544..2204644 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IMY14_RS11245 (2200304)	2200304..2200525	-	222	WP_128751206.1	hypothetical protein	-
IMY14_RS11250 (2200522)	2200522..2200923	-	402	WP_128751207.1	hypothetical protein	-
IMY14_RS11255 (2200969)	2200969..2201406	-	438	WP_128751208.1	hypothetical protein	-
IMY14_RS11260 (2201722)	2201722..2202939	-	1218	WP_174616712.1	hypothetical protein	-
IMY14_RS11265 (2202958)	2202958..2203803	-	846	WP_128751210.1	GIY-YIG nuclease family protein	-
IMY14_RS11270 (2203924)	2203924..2204112	-	189	WP_128751211.1	hypothetical protein	-
IMY14_RS11275 (2204157)	2204157..2204408	-	252	WP_080010576.1	hypothetical protein	-
IMY14_RS11280 (2204427)	2204427..2204603	-	177	WP_019712271.1	hypothetical protein	Toxin
- (2204544)	2204544..2204644	+	101	NuclAT_0	-	Antitoxin
- (2204544)	2204544..2204644	+	101	NuclAT_0	-	Antitoxin
- (2204544)	2204544..2204644	+	101	NuclAT_0	-	Antitoxin
- (2204544)	2204544..2204644	+	101	NuclAT_0	-	Antitoxin
IMY14_RS11285 (2205144)	2205144..2205755	-	612	WP_074794693.1	hypothetical protein	-
IMY14_RS11290 (2205956)	2205956..2206285	-	330	WP_032721651.1	helix-turn-helix transcriptional regulator	-
IMY14_RS11295 (2207240)	2207240..2207434	+	195	WP_072692657.1	hypothetical protein	-
IMY14_RS11300 (2207474)	2207474..2209348	+	1875	Protein_2188	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2135246..2266855	131609

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6864.42 Da
• Isoelectric Point: 12.8833

>T177627 WP_019712271.1 NZ_CP063150:c2204603-2204427 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T177627 NZ_CP083610:c402838-402497 [Escherichia coli]
ATGAAAACTTTACCTGCAATAACTCAGCGGGCGGTGAAGCCCTGCCTGTCACCCGTGGCTGTCTGGCAAATGTTACTGAC
ACGTCTGCTGGAACAGCACTATGGTCTGACAATAAACGACACGCCATTCTGCAATGAGGCTGTGATTAAGGAACACATCG
ATGCCGGTATCACCCTAGCCGATGCCGTGAATTTTCTGGTAGAAAAATACGAGCTGGTTCGTATCGACAGGAAGGGATTT
AGCTGGCAGGAACAATCTCCTTATCTCCGGGCTGCAGACATTCTGCGAGCGCGGCAGGCAACTGGCTTGTTGCGGCAAAG
CCGTAACAACGTAGTACGATGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT177627 NZ_CP063150:2204544-2204644 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGAAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Antitoxin