Detailed information of TA system TA177621

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2204157..2204486
• Replicon: chromosome
• Accession: NZ_CP063150
• Organism: Bacillus subtilis strain s-16

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: IMY14_RS11275
• Protein ID: WP_080010576.1
• Coordinates: 2204157..2204408 (-)
• Length: 84 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2204386..2204486 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IMY14_RS11245	2200304..2200525	-	222	WP_128751206.1	hypothetical protein	-
IMY14_RS11250	2200522..2200923	-	402	WP_128751207.1	hypothetical protein	-
IMY14_RS11255	2200969..2201406	-	438	WP_128751208.1	hypothetical protein	-
IMY14_RS11260	2201722..2202939	-	1218	WP_174616712.1	hypothetical protein	-
IMY14_RS11265	2202958..2203803	-	846	WP_128751210.1	GIY-YIG nuclease family protein	-
IMY14_RS11270	2203924..2204112	-	189	WP_128751211.1	hypothetical protein	-
IMY14_RS11275	2204157..2204408	-	252	WP_080010576.1	hypothetical protein	Toxin
-	2204386..2204486	+	101	-	-	Antitoxin
IMY14_RS11280	2204427..2204603	-	177	WP_019712271.1	hypothetical protein	-
-	2204544..2204644	+	101	NuclAT_0	-	-
-	2204544..2204644	+	101	NuclAT_0	-	-
-	2204544..2204644	+	101	NuclAT_0	-	-
-	2204544..2204644	+	101	NuclAT_0	-	-
IMY14_RS11285	2205144..2205755	-	612	WP_074794693.1	hypothetical protein	-
IMY14_RS11290	2205956..2206285	-	330	WP_032721651.1	helix-turn-helix transcriptional regulator	-
IMY14_RS11295	2207240..2207434	+	195	WP_072692657.1	hypothetical protein	-
IMY14_RS11300	2207474..2209348	+	1875	Protein_2188	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2135246..2266855	131609

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 10071.13 Da
• Isoelectric Point: 10.0301

>T177621 WP_080010576.1 NZ_CP063150:c2204408-2204157 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEAQTLINIIFIVTCIIAILLWIIYFVFLKLRN
KSH

Nucleotide

• Length: 252 bp

>T177621 NZ_CP083604:c1117841-1117569 [Macrococcus armenti]
ATGCCTAAGAAAAAGATACTATTTTATTCAGGTGGTTTTGAAGATTATACGTATTGGCAAACTAACGATAAAACTGTATT
AAAGAAAATAAAAAAACTAATAAAGAGTATTATGATTGATGGTGCAAATGAAGGTATAGGTAAGCCAGAAAAATTATTAG
GAAACTATACAGGTTGCTATAGCAGAAGGATCACTCATGAACATAGGCTCGTATATAAGATAGAAGATGATTCAATATGT
ATTTTACAATGTCGTTTTCATTATAAAAGGTAG

Antitoxin

Nucleotide

• Length: 101 bp

>AT177621 NZ_CP063150:2204386-2204486 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Antitoxin