Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/- |
Location | 1485767..1486421 | Replicon | chromosome |
Accession | NZ_CP063073 | ||
Organism | Pseudomonas poae strain PMA22 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | IMF22_RS06945 | Protein ID | WP_159957548.1 |
Coordinates | 1486071..1486421 (-) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | IMF22_RS06940 | Protein ID | WP_197627696.1 |
Coordinates | 1485767..1486081 (-) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IMF22_RS06930 | 1481331..1484894 | + | 3564 | WP_197627694.1 | type VI secretion system membrane subunit TssM | - |
IMF22_RS06935 | 1484904..1485566 | + | 663 | WP_197627695.1 | type VI secretion system-associated protein TagF | - |
IMF22_RS06940 | 1485767..1486081 | - | 315 | WP_197627696.1 | transcriptional regulator | Antitoxin |
IMF22_RS06945 | 1486071..1486421 | - | 351 | WP_159957548.1 | toxin | Toxin |
IMF22_RS06950 | 1486656..1488251 | - | 1596 | WP_197627697.1 | gamma-glutamyltransferase family protein | - |
IMF22_RS06955 | 1489502..1490965 | - | 1464 | WP_106579876.1 | NADH-quinone oxidoreductase subunit NuoN | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 13712.59 Da Isoelectric Point: 9.7549
>T177577 WP_159957548.1 NZ_CP063073:c1486421-1486071 [Pseudomonas poae]
MDALFIELPAFERHRKDYLSDALFQGFQQELMRNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLAPHHKKALKHLLDREIKARTQHET
MDALFIELPAFERHRKDYLSDALFQGFQQELMRNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLAPHHKKALKHLLDREIKARTQHET
Download Length: 351 bp
>T177577 NZ_CP083585:179079-179186 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGTCTCCGGTCATTGATGACATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGTCTCCGGTCATTGATGACATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11675.49 Da Isoelectric Point: 10.7906
>AT177577 WP_197627696.1 NZ_CP063073:c1486081-1485767 [Pseudomonas poae]
MKREIFSELVEGFGALADERQGKVTLRTHKVQLNNLAPLTAEEVVAVRQQLNLSRSVFAMYLRTNLRTLENWEQGRAKPN
AQATTLIRLVARFPETVAQLAALG
MKREIFSELVEGFGALADERQGKVTLRTHKVQLNNLAPLTAEEVVAVRQQLNLSRSVFAMYLRTNLRTLENWEQGRAKPN
AQATTLIRLVARFPETVAQLAALG
Download Length: 315 bp
>AT177577 NZ_CP083585:c179031-178965 [Escherichia coli]
GGTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
GGTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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