Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 178302..178812 Replicon chromosome
Accession NZ_CP063050
Organism Photobacterium damselae subsp. damselae strain KC-Dl-1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag IL982_RS15270 Protein ID WP_086368444.1
Coordinates 178302..178562 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2T3QIT0
Locus tag IL982_RS15275 Protein ID WP_036765838.1
Coordinates 178552..178812 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IL982_RS15245 174143..174721 + 579 Protein_163 substrate binding domain-containing protein -
IL982_RS15250 174783..175619 - 837 WP_188013011.1 HNH endonuclease -
IL982_RS15255 175804..176952 - 1149 WP_086368441.1 iron-containing alcohol dehydrogenase -
IL982_RS15260 177112..177996 + 885 WP_086368442.1 AraC family transcriptional regulator -
IL982_RS15265 178008..178262 + 255 WP_188013012.1 hypothetical protein -
IL982_RS15270 178302..178562 - 261 WP_086368444.1 Txe/YoeB family addiction module toxin Toxin
IL982_RS15275 178552..178812 - 261 WP_036765838.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IL982_RS15280 179006..180688 - 1683 WP_086368560.1 RluA family pseudouridine synthase -
IL982_RS15285 180763..181152 - 390 WP_086368445.1 hypothetical protein -
IL982_RS15290 181429..182046 - 618 WP_151182532.1 TPM domain-containing protein -
IL982_RS15295 182049..182804 - 756 WP_086368447.1 TPM domain-containing protein -
IL982_RS15300 182805..183404 - 600 WP_065171320.1 LemA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10318.87 Da        Isoelectric Point: 9.9416

>T177567 WP_086368444.1 NZ_CP063050:c178562-178302 [Photobacterium damselae subsp. damselae]
MMINFTPNAWDDYLYWQSQDKKTLKRINKLIENCVRTPFEGIGKPEPLKDNLSGYWSRRIDDTHRLVYKATQNTLVIVAV
RFHYQK

Download         Length: 261 bp

>T177567 NZ_CP083575:c4519200-4519048 [Xanthomonas phaseoli pv. manihotis]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAGTGCAGCGACGGTAAGTGCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9718.89 Da        Isoelectric Point: 4.3167

>AT177567 WP_036765838.1 NZ_CP063050:c178812-178552 [Photobacterium damselae subsp. damselae]
MTVLSFSEVRGNFKKVCDQVVDDCDAVVIHRRDADNVVLMSESEFNSWKETMYLMSNPVNAANLLESIKQAECGNVQTHE
LLSHDD

Download         Length: 261 bp

>AT177567 NZ_CP083575:c4518973-4518839 [Xanthomonas phaseoli pv. manihotis]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2T3QIT0

References