Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 1344484..1344705 Replicon chromosome
Accession NZ_CP062985
Organism Escherichia coli UTI89

Toxin (Protein)


Gene name ldrD Uniprot ID S1PGT3
Locus tag IIE08_RS06600 Protein ID WP_000170954.1
Coordinates 1344484..1344591 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 1344644..1344705 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IIE08_RS06575 1340329..1341411 + 1083 WP_000804726.1 peptide chain release factor 1 -
IIE08_RS06580 1341411..1342244 + 834 WP_000456474.1 peptide chain release factor N(5)-glutamine methyltransferase -
IIE08_RS06585 1342241..1342633 + 393 WP_000200375.1 invasion regulator SirB2 -
IIE08_RS06590 1342637..1343446 + 810 WP_001257054.1 invasion regulator SirB1 -
IIE08_RS06595 1343482..1344336 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
IIE08_RS06600 1344484..1344591 - 108 WP_000170954.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 1344644..1344705 + 62 NuclAT_12 - Antitoxin
- 1344644..1344705 + 62 NuclAT_12 - Antitoxin
- 1344644..1344705 + 62 NuclAT_12 - Antitoxin
- 1344644..1344705 + 62 NuclAT_12 - Antitoxin
- 1344644..1344705 + 62 NuclAT_13 - Antitoxin
- 1344644..1344705 + 62 NuclAT_13 - Antitoxin
- 1344644..1344705 + 62 NuclAT_13 - Antitoxin
- 1344644..1344705 + 62 NuclAT_13 - Antitoxin
- 1344644..1344705 + 62 NuclAT_14 - Antitoxin
- 1344644..1344705 + 62 NuclAT_14 - Antitoxin
- 1344644..1344705 + 62 NuclAT_14 - Antitoxin
- 1344644..1344705 + 62 NuclAT_14 - Antitoxin
- 1344644..1344705 + 62 NuclAT_15 - Antitoxin
- 1344644..1344705 + 62 NuclAT_15 - Antitoxin
- 1344644..1344705 + 62 NuclAT_15 - Antitoxin
- 1344644..1344705 + 62 NuclAT_15 - Antitoxin
- 1344644..1344705 + 62 NuclAT_16 - Antitoxin
- 1344644..1344705 + 62 NuclAT_16 - Antitoxin
- 1344644..1344705 + 62 NuclAT_16 - Antitoxin
- 1344644..1344705 + 62 NuclAT_16 - Antitoxin
- 1344644..1344705 + 62 NuclAT_17 - Antitoxin
- 1344644..1344705 + 62 NuclAT_17 - Antitoxin
- 1344644..1344705 + 62 NuclAT_17 - Antitoxin
- 1344644..1344705 + 62 NuclAT_17 - Antitoxin
- 1344644..1344706 + 63 NuclAT_10 - -
- 1344644..1344706 + 63 NuclAT_10 - -
- 1344644..1344706 + 63 NuclAT_10 - -
- 1344644..1344706 + 63 NuclAT_10 - -
- 1344644..1344706 + 63 NuclAT_11 - -
- 1344644..1344706 + 63 NuclAT_11 - -
- 1344644..1344706 + 63 NuclAT_11 - -
- 1344644..1344706 + 63 NuclAT_11 - -
- 1344644..1344706 + 63 NuclAT_6 - -
- 1344644..1344706 + 63 NuclAT_6 - -
- 1344644..1344706 + 63 NuclAT_6 - -
- 1344644..1344706 + 63 NuclAT_6 - -
- 1344644..1344706 + 63 NuclAT_7 - -
- 1344644..1344706 + 63 NuclAT_7 - -
- 1344644..1344706 + 63 NuclAT_7 - -
- 1344644..1344706 + 63 NuclAT_7 - -
- 1344644..1344706 + 63 NuclAT_8 - -
- 1344644..1344706 + 63 NuclAT_8 - -
- 1344644..1344706 + 63 NuclAT_8 - -
- 1344644..1344706 + 63 NuclAT_8 - -
- 1344644..1344706 + 63 NuclAT_9 - -
- 1344644..1344706 + 63 NuclAT_9 - -
- 1344644..1344706 + 63 NuclAT_9 - -
- 1344644..1344706 + 63 NuclAT_9 - -
- 1344644..1344707 + 64 NuclAT_18 - -
- 1344644..1344707 + 64 NuclAT_18 - -
- 1344644..1344707 + 64 NuclAT_18 - -
- 1344644..1344707 + 64 NuclAT_18 - -
- 1344644..1344707 + 64 NuclAT_19 - -
- 1344644..1344707 + 64 NuclAT_19 - -
- 1344644..1344707 + 64 NuclAT_19 - -
- 1344644..1344707 + 64 NuclAT_19 - -
- 1344644..1344707 + 64 NuclAT_20 - -
- 1344644..1344707 + 64 NuclAT_20 - -
- 1344644..1344707 + 64 NuclAT_20 - -
- 1344644..1344707 + 64 NuclAT_20 - -
- 1344644..1344707 + 64 NuclAT_21 - -
- 1344644..1344707 + 64 NuclAT_21 - -
- 1344644..1344707 + 64 NuclAT_21 - -
- 1344644..1344707 + 64 NuclAT_21 - -
- 1344644..1344707 + 64 NuclAT_22 - -
- 1344644..1344707 + 64 NuclAT_22 - -
- 1344644..1344707 + 64 NuclAT_22 - -
- 1344644..1344707 + 64 NuclAT_22 - -
- 1344644..1344707 + 64 NuclAT_23 - -
- 1344644..1344707 + 64 NuclAT_23 - -
- 1344644..1344707 + 64 NuclAT_23 - -
- 1344644..1344707 + 64 NuclAT_23 - -
IIE08_RS06605 1344997..1346097 - 1101 WP_001313768.1 sodium-potassium/proton antiporter ChaA -
IIE08_RS06610 1346367..1346597 + 231 WP_001146444.1 putative cation transport regulator ChaB -
IIE08_RS06615 1346755..1347450 + 696 WP_000632706.1 glutathione-specific gamma-glutamylcyclotransferase -
IIE08_RS06620 1347494..1347847 - 354 WP_001169659.1 DsrE/F sulfur relay family protein YchN -
IIE08_RS06625 1348032..1349426 + 1395 WP_000086194.1 inverse autotransporter invasin YchO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3983.80 Da        Isoelectric Point: 11.4779

>T177380 WP_000170954.1 NZ_CP062985:c1344591-1344484 [Escherichia coli UTI89]
MTLAQFAMIFWHDLAAPILAGIITAAIVGWWRNRK

Download         Length: 108 bp

>T177380 NZ_CP062985:c1344591-1344484 [Escherichia coli UTI89]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 62 bp

>AT177380 NZ_CP062985:1344644-1344705 [Escherichia coli UTI89]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U9LPE9

Antitoxin

Download structure file

References