Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 997552..998072 Replicon chromosome
Accession NZ_CP062950
Organism Bifidobacterium longum subsp. longum strain JCM 11341

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BL1341_RS04535 Protein ID WP_117701510.1
Coordinates 997818..998072 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BL1341_RS04530 Protein ID WP_117701509.1
Coordinates 997552..997818 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BL1341_RS04510 994799..995116 + 318 WP_131207568.1 HigA family addiction module antidote protein -
BL1341_RS04515 995384..996238 + 855 WP_193027419.1 hypothetical protein -
BL1341_RS04520 996615..996980 - 366 WP_193027342.1 hypothetical protein -
BL1341_RS04525 997003..997383 - 381 WP_193027343.1 hypothetical protein -
BL1341_RS04530 997552..997818 + 267 WP_117701509.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BL1341_RS04535 997818..998072 + 255 WP_117701510.1 Txe/YoeB family addiction module toxin Toxin
BL1341_RS04540 998176..999165 - 990 WP_193027345.1 hypothetical protein -
BL1341_RS04545 999365..999632 - 268 Protein_886 hypothetical protein -
BL1341_RS04550 999643..1000191 - 549 WP_193027347.1 hypothetical protein -
BL1341_RS04555 1000430..1000675 + 246 WP_007053507.1 hypothetical protein -
BL1341_RS04560 1000764..1002440 + 1677 WP_100969855.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 995384..1052579 57195


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9863.31 Da        Isoelectric Point: 8.2604

>T177357 WP_117701510.1 NZ_CP062950:997818-998072 [Bifidobacterium longum subsp. longum]
MLLCWTDDAWADYLYWQSQDRKTLKRINALIRDMQRTPFEGIGKPEPLRCGLSGAWSRRIDSANRIIYTVADDRLCILSA
KDHY

Download         Length: 255 bp

>T177357 NZ_CP083451:1932200-1932616 [Comamonas odontotermitis]
ATGCCCCGTTATTACCTCGACACCAATATTTGCATCTATGCCTGGCATCGGCAACACGCTGCCGTGCTGGCTCGCATGCG
TGCCGTCGATCACACCAGAATGGTGATATCCGCGCTGGTGGCGGCGGAGTTGGCCAGTGGTGTCATGCGCAGCACGCATG
TAGAGCGTAATCGCGTGTTGATGGAAGAAGCCTTGTCACTATTTTCGATTGAGCCCTGGGGCGGCGATGCCATCTGGCAT
TACGGCGAGCAATCCGCTCGCCTGCGCAAGGCGGGCACCCCCATCGGTGCCATCGATCTCATGATTGGATGCCAGGCCCT
GGCCGACCCTGACGGCGTGCTGGTCACGCACAACGTGCGCGAATTCGAGCGGATCGAAGGCCTGCGGATCGAGGACTGGA
TGGAGGCTGCCGAGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9911.09 Da        Isoelectric Point: 4.3417

>AT177357 WP_117701509.1 NZ_CP062950:997552-997818 [Bifidobacterium longum subsp. longum]
MTQAVAYSNFRANLKTYMRRVNEDADTLLVTNADPEDNVVVMSADDYDSLMETLRVYQNPYLSDKVTRGMAQVRQGQTMA
RDLVEAGA

Download         Length: 267 bp

>AT177357 NZ_CP083451:1931919-1932176 [Comamonas odontotermitis]
ATGTCCGATCTCGCCATCGCCAAAGTCTTCATGAACGGCCGCAGCCAGGCGGTTCGCCTGCCCAAGGAGTTCCGCTTCGA
TACCGAGGAGGTGACGGTGGAGCGCCAGGCCGATGGCGCTGTAGTTCTGCGTCCGGTGCCAGCGGATGCGCATGCCGCGT
GGCTGGCTCGGCTGGACAAGGTGCTGGGCCGCTTTGAAGGCATGCCCGACGAGATCGAGCGCGACAAGACGCCGCCACGC
GATGTCGGTTTTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References