Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1850464..1851124 Replicon chromosome
Accession NZ_CP062916
Organism Raoultella terrigena strain Res13-Abat-PEB01-P1-04-A

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag IMO34_RS08585 Protein ID WP_195710912.1
Coordinates 1850464..1850817 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IMO34_RS08590 Protein ID WP_041146308.1
Coordinates 1850822..1851124 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMO34_RS08575 1846982..1847413 + 432 WP_115192342.1 universal stress protein -
IMO34_RS08580 1847464..1850151 + 2688 WP_115192343.1 cation-transporting P-type ATPase -
IMO34_RS08585 1850464..1850817 + 354 WP_195710912.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IMO34_RS08590 1850822..1851124 + 303 WP_041146308.1 XRE family transcriptional regulator Antitoxin
IMO34_RS08595 1851365..1852639 - 1275 WP_123551637.1 beta-ketoacyl-ACP synthase II -
IMO34_RS08600 1852659..1854221 - 1563 WP_041146306.1 DHA2 family efflux MFS transporter permease subunit -
IMO34_RS08605 1854238..1855261 - 1024 Protein_1678 HlyD family secretion protein -
IMO34_RS08610 1855245..1855802 - 558 WP_041146304.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-79)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13382.37 Da        Isoelectric Point: 7.6330

>T177307 WP_195710912.1 NZ_CP062916:1850464-1850817 [Raoultella terrigena]
VWIIKTTDRFDGWFSTLCATDRACVLALLLVLRERGPGLSRPYADTLKGSCYGNMKELRVQSRGDPIRVFFAFDPFRAGI
LLCAGHKVGNEKRFYEQTIPIADREFTDYLNTLDDKE

Download         Length: 354 bp

>T177307 NZ_CP083436:468486-468836 [Bacillus velezensis]
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAAAATGATATCGGAAATCGCTTTAGCCCGACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCCT
GCAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11013.75 Da        Isoelectric Point: 5.7251

>AT177307 WP_041146308.1 NZ_CP062916:1850822-1851124 [Raoultella terrigena]
MGRTLEQLLADEKPEVVADAQAMATDILLNIHLAELREKVQKTQVEMAQALGIRQPTVASMEKQGRDLKLSTLKRYVEAA
GGKLRLDVELPDGSHFGFAL

Download         Length: 303 bp

>AT177307 NZ_CP083436:468199-468480 [Bacillus velezensis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATCTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACCGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References