Detailed information of TA system TA175414

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 3468861..3469086
• Replicon: chromosome
• Accession: NZ_CP062702
• Organism: Escherichia coli O157:H7 strain Z1834

Toxin (Protein)

• Gene name: hokW
• Uniprot ID: -
• Locus tag: ILQ62_RS17730
• Protein ID: WP_000813263.1
• Coordinates: 3468861..3469016 (-)
• Length: 52 a.a.

Antitoxin (RNA)

Gene name	sokW
Locus tag	-
Coordinates	3469028..3469086 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-47)

Sequences

Toxin

Protein

• Length: 52 a.a.
• Molecular weight: 5722.86 Da
• Isoelectric Point: 6.1531

>T175414 WP_000813263.1 NZ_CP062702:c3469016-3468861 [Escherichia coli O157:H7]
MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRVRTGQTEVAVFTAYEPEE

Nucleotide

• Length: 156 bp

>T175414 NZ_CP081903:6256294-6256563 [Bacteroides cellulosilyticus]
ATGAAAGTAATATTTTCACCTCTTGCTATGGAGCAATGGGAGTACTGGAAGAAAAACAATCCTAATATTGCCAAACGCAT
CAAGAAGATTCTTCTCGACATTAGAGAGCATCCTTATACAGGAATCGCAAAGCCAGAACCTCTTAAATATGATTTAGCGG
GTAAATGGTCAAGACGCATCAATGAGGAACATAGGATTATTTACTCTGTAAATGATGACAGAATAGAGATTGATATACTA
TCAATGAGATACCATTACTCCAAGAAGTAA

Antitoxin

Nucleotide

• Length: 59 bp

>AT175414 NZ_CP062702:3469028-3469086 [Escherichia coli O157:H7]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTAGATTTGCCGTTCATAGATTGAGCCTCA

Structures

Antitoxin