Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 1057949..1058146 Replicon chromosome
Accession NZ_CP062471
Organism Staphylococcus aureus strain MRSA - AMRF 3

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ILP75_RS05280 Protein ID WP_001802298.1
Coordinates 1058042..1058146 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1057949..1057987 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILP75_RS05260 1054136..1054801 - 666 WP_001024095.1 SDR family oxidoreductase -
ILP75_RS05265 1054953..1055273 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ILP75_RS05270 1055275..1056252 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
ILP75_RS05275 1056518..1057609 + 1092 WP_000495669.1 hypothetical protein -
- 1057949..1057987 + 39 - - Antitoxin
ILP75_RS05280 1058042..1058146 - 105 WP_001802298.1 hypothetical protein Toxin
ILP75_RS05285 1058826..1058984 + 159 WP_001792784.1 hypothetical protein -
ILP75_RS05290 1059642..1060499 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
ILP75_RS05295 1060567..1061349 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T175326 WP_001802298.1 NZ_CP062471:c1058146-1058042 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T175326 NZ_CP081889:3922720-3922938 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 39 bp

>AT175326 NZ_CP062471:1057949-1057987 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References