Detailed information of TA system TA175249

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 179937..180119
• Replicon: chromosome
• Accession: NZ_CP062439
• Organism: Staphylococcus aureus strain NAS_AN_285

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF743_RS01080
• Protein ID: WP_001801861.1
• Coordinates: 180024..180119 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	179937..179996 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF743_RS01065	179075..179452	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
IF743_RS01070	179646..179822	+	177	Protein_177	transposase	-
IF743_RS01075	179800..179901	-	102	WP_001791893.1	hypothetical protein	-
-	179937..179996	+	60	-	-	Antitoxin
IF743_RS01080	180024..180119	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF743_RS01085	180322..180465	+	144	WP_001549059.1	transposase	-
IF743_RS01090	181069..181452	+	384	WP_000070811.1	hypothetical protein	-
IF743_RS01095	181463..181639	+	177	WP_000375476.1	hypothetical protein	-
IF743_RS01100	181641..181826	+	186	WP_000809857.1	hypothetical protein	-
IF743_RS01105	181940..182581	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
IF743_RS01110	182799..183350	-	552	WP_000414205.1	hypothetical protein	-
IF743_RS01115	183448..183792	-	345	WP_000627551.1	DUF3969 family protein	-
IF743_RS01120	183833..184459	-	627	Protein_187	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	161417..206145	44728

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T175249 WP_001801861.1 NZ_CP062439:c180119-180024 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T175249 NZ_CP081858:59907-60218 [Salmonella enterica subsp. enterica serovar Schwarzengrund]
ATGCAATTCATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGATGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGCAGTGGCGTACGAATTATCTATTTTCATCGTAGTCAACGGTATGAGGTTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT175249 NZ_CP062439:179937-179996 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin