Detailed information of TA system TA175235

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2299505..2299689
• Replicon: chromosome
• Accession: NZ_CP062421
• Organism: Staphylococcus aureus strain NAS_AN_003

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: IF693_RS11215
• Protein ID: WP_072467491.1
• Coordinates: 2299505..2299612 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2299629..2299689 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF693_RS11190	2294878..2295351	+	474	WP_000456489.1	GyrI-like domain-containing protein	-
IF693_RS11195	2295474..2296685	-	1212	WP_001192075.1	multidrug effflux MFS transporter	-
IF693_RS11200	2296867..2297526	-	660	WP_000831298.1	membrane protein	-
IF693_RS11205	2297586..2298728	-	1143	WP_001176873.1	glycerate kinase	-
IF693_RS11210	2298985..2299371	+	387	WP_000779348.1	flippase GtxA	-
IF693_RS11215	2299505..2299612	+	108	WP_072467491.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2299629..2299689	-	61	-	-	Antitoxin
IF693_RS11220	2300202..2301965	+	1764	WP_001064834.1	ABC transporter ATP-binding protein	-
IF693_RS11225	2301990..2303723	+	1734	WP_000486502.1	ABC transporter ATP-binding protein	-
IF693_RS11230	2303954..2304121	+	168	WP_031866196.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3944.67 Da
• Isoelectric Point: 10.4934

>T175235 WP_072467491.1 NZ_CP062421:2299505-2299612 [Staphylococcus aureus]
IFNLLIDIMTSAISGCLVAFFANWLRTRSNKKGDK

Nucleotide

• Length: 108 bp

>T175235 NZ_CP081828:58981-59397 [Klebsiella quasipneumoniae]
ATGAAGAAAACCTGGATGCTCGACACTAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGTGATCGCATCGTGGTCTCGGCCGTGACGTATGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCCATCCTGCCCTGGGACCGCGCC
GCGGTGGATGCCACGACGGACATCCGGGTGGCGCTGCGCTTCGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCGGCCGGCGCAGTCCTGGTGACGAACAATGTGAGAGAGTTTGAGCGGGTGCCGGGTCTGGTTCTGG
AAGACTGGGTTAAGTAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT175235 NZ_CP062421:c2299689-2299629 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin