Detailed information of TA system TA175159

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2310996..2311180
• Replicon: chromosome
• Accession: NZ_CP062416
• Organism: Staphylococcus aureus strain NAS_AN_149

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: Q2FVI9
• Locus tag: IF719_RS11235
• Protein ID: WP_000482650.1
• Coordinates: 2310996..2311103 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2311120..2311180 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4011.78 Da
• Isoelectric Point: 11.0582

>T175159 WP_000482650.1 NZ_CP062416:2310996-2311103 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T175159 NZ_CP081789:1929-2966 [Escherichia coli]
ATGGCACAGAACCCATTTAAAGCACTAAATATTAATACAGACAAGATTGAAGCTGCCTTGACGCAGAATGGCGTCACAAA
CTTTTCTTCTATCGTGAGAAACGAAAGAGAAACACATTTATCAGGGACATATAAAGAAATAGATTTTTTAATAAAGCTAA
TGCCATCAGGTGGAAACACCACTATAGGAAGGGCATCAGGACAAAACAACACTTACTTTGATGAGATCGCTGGCATTATA
AAAGAAAACTGTTTGTATTCAGATAAAAAAACGTTTGAATACACAATCCCAAGATTCAGCGATGAAAATAAGGAAATGTT
GTTTGCATTTCTTACTGAAGAAAACGTAAAAATAGAAGAAGATAAAAACAACGACCCCAACTGTAAACATCAATACATCA
TGACCACTGGCAATGGTGACAGAGTCAGAGCAAAAATTTACAACCGTGGCTCAATTCAATTCCAAGGTAAATATCTTCAA
ATCGCAAGTTTGATTAATGATTTCATGTGCACCATACTGGACATGAAAGAGATTATAGAACAGAAGAATCAAGAATTTAA
TGTTGACATAAAAAAAGAAACAATTGAGTCAGAATTACATAGTAAACTACCAAAAAGCATCGACCTAATCCATGACGACA
TCAAAAAACAGCTATCCTGCTCGCTCATAATGAAACAAATAGATGTCGAAATGGAAGATTACTCAACATATTGTTTCTCA
GCCTTAAGATCCATAGAAGGCTTTATATATCAACTACTTGGAAGCGTATGCAACCCATCATCATCAAGGAATCTTGGCGA
GTACTTCACTGAGAATAACCCGAAATACATAATAAGAGATATACACCAAGAAACTATTAATGGTGAAATAGCAGAAGTTT
TGTGTGAGTGCTACACTTACTGGCATGAAAACAGACATGGCTTGTTCCATATGAAACCAGGTGTGGCTGACACTAAGACA
ATTGACAAAGCAGAATCTATTGAAATTATCGATACTGTATGTCAGTTGATAGATAAAGGCATGGCTAGGTTGAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT175159 NZ_CP062416:c2311180-2311120 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2C9TTS8

Antitoxin