Detailed information of TA system TA175144

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2734074..2734336
• Replicon: chromosome
• Accession: NZ_CP062415
• Organism: Staphylococcus aureus strain NAS_AN_150

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: IF720_RS13565
• Protein ID: WP_073392962.1
• Coordinates: 2734074..2734178 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	2734173..2734336 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF720_RS13550	2730870..2731652	+	783	WP_000908186.1	ABC transporter ATP-binding protein	-
IF720_RS13555	2731720..2732577	+	858	WP_240111983.1	HAD family hydrolase	-
IF720_RS13560	2733236..2733394	-	159	WP_001792784.1	hypothetical protein	-
IF720_RS13565	2734074..2734178	+	105	WP_073392962.1	hypothetical protein	Toxin
-	2734173..2734336	-	164	-	-	Antitoxin
IF720_RS13575	2734604..2736250	-	1647	WP_000277741.1	IS1182-like element ISSau3 family transposase	-
IF720_RS13580	2736538..2737629	-	1092	WP_000495684.1	hypothetical protein	-
IF720_RS13585	2737895..2738875	-	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
IF720_RS13590	2738877..2739197	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2734604..2736250	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T175144 WP_073392962.1 NZ_CP062415:2734074-2734178 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T175144 NZ_CP081782:c2705470-2705294 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin

Nucleotide

• Length: 164 bp

>AT175144 NZ_CP062415:c2734336-2734173 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Structures

Antitoxin