Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 2612883..2613145 | Replicon | chromosome |
Accession | NZ_CP062411 | ||
Organism | Staphylococcus aureus strain NAS_AN_204 |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | Q2FWA7 |
Locus tag | IF728_RS12975 | Protein ID | WP_001802298.1 |
Coordinates | 2612883..2612987 (+) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF2 | ||
Locus tag | - | ||
Coordinates | 2612982..2613145 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IF728_RS12955 | 2609680..2610462 | + | 783 | WP_000908182.1 | ABC transporter ATP-binding protein | - |
IF728_RS12960 | 2610530..2611387 | + | 858 | WP_000370925.1 | Cof-type HAD-IIB family hydrolase | - |
IF728_RS12965 | 2612045..2612203 | - | 159 | WP_001792784.1 | hypothetical protein | - |
IF728_RS12970 | 2612196..2612366 | - | 171 | WP_240053154.1 | hypothetical protein | - |
IF728_RS12975 | 2612883..2612987 | + | 105 | WP_001802298.1 | hypothetical protein | Toxin |
- | 2612982..2613145 | - | 164 | - | - | Antitoxin |
IF728_RS12985 | 2613420..2614511 | - | 1092 | WP_000495669.1 | hypothetical protein | - |
IF728_RS12990 | 2614777..2615754 | - | 978 | WP_000019734.1 | CDF family zinc efflux transporter CzrB | - |
IF728_RS12995 | 2615756..2616076 | - | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
IF728_RS13000 | 2616228..2616893 | + | 666 | WP_001024095.1 | SDR family oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T175067 WP_001802298.1 NZ_CP062411:2612883-2612987 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T175067 NZ_CP081762:2937554-2937661 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGGACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGGACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 164 bp
>AT175067 NZ_CP062411:c2613145-2612982 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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