Detailed information of TA system TA174960

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1915613..1915829
• Replicon: chromosome
• Accession: NZ_CP062405
• Organism: Staphylococcus aureus strain NAS_NP_209

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: IF754_RS09750
• Protein ID: WP_073392962.1
• Coordinates: 1915725..1915829 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1915613..1915668 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF754_RS09725	1910706..1911026	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
IF754_RS09730	1911028..1912008	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
IF754_RS09735	1912274..1913365	+	1092	WP_000495684.1	hypothetical protein	-
IF754_RS09740	1913653..1915299	+	1647	WP_000277741.1	IS1182-like element ISSau3 family transposase	-
-	1915613..1915668	+	56	-	-	Antitoxin
IF754_RS09750	1915725..1915829	-	105	WP_073392962.1	hypothetical protein	Toxin
IF754_RS09755	1916509..1916667	+	159	WP_001792784.1	hypothetical protein	-
IF754_RS09760	1917326..1918183	-	858	WP_000370937.1	HAD family hydrolase	-
IF754_RS09765	1918251..1919033	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1913653..1915299	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T174960 WP_073392962.1 NZ_CP062405:c1915829-1915725 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T174960 NZ_CP081713:4424539-4424916 [Escherichia coli]
ATGAAAACATTACCCGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTGTC
CCGGTTGCTGGACCAGCATTACGGCCTTACGCTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGTATTGATATTCTCCGGGCTCGCAGGGCAACCGGCCTGATGACCCGCGA
TAACTACAGAACGGTAAATAACATTACCCAGGGGAAGCATCCGGAGGCGAAACAATGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT174960 NZ_CP062405:1915613-1915668 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin