Detailed information of TA system TA174955

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1611535..1611715
• Replicon: chromosome
• Accession: NZ_CP062405
• Organism: Staphylococcus aureus strain NAS_NP_209

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF754_RS08030
• Protein ID: WP_001801861.1
• Coordinates: 1611535..1611630 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1611658..1611715 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF754_RS08000	1606679..1607305	+	627	WP_000669038.1	hypothetical protein	-
IF754_RS08005	1607346..1607690	+	345	WP_000627550.1	DUF3969 family protein	-
IF754_RS08010	1607788..1608360	+	573	WP_000414222.1	hypothetical protein	-
IF754_RS08015	1608509..1609876	-	1368	WP_001093574.1	FRG domain-containing protein	-
IF754_RS08020	1609876..1610445	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
IF754_RS08025	1610638..1611084	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
IF754_RS08030	1611535..1611630	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1611658..1611715	-	58	-	-	Antitoxin
IF754_RS08035	1611753..1611854	+	102	WP_001791232.1	hypothetical protein	-
IF754_RS08040	1612029..1612472	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
IF754_RS08045	1612472..1612915	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
IF754_RS08050	1612915..1613357	-	443	Protein_1585	DUF1433 domain-containing protein	-
IF754_RS08055	1613882..1616302	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hysA	1604120..1641478	37358

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174955 WP_001801861.1 NZ_CP062405:1611535-1611630 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174955 NZ_CP081713:3668031-3668249 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTTTGGAAATTTATTCGCTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT174955 NZ_CP062405:c1611715-1611658 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin