Detailed information of TA system TA174943

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1874694..1874910
• Replicon: chromosome
• Accession: NZ_CP062404
• Organism: Staphylococcus aureus strain NAS_NP_229

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: IF757_RS09415
• Protein ID: WP_073392962.1
• Coordinates: 1874806..1874910 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1874694..1874749 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF757_RS09390	1869787..1870107	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
IF757_RS09395	1870109..1871089	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
IF757_RS09400	1871355..1872446	+	1092	WP_000495684.1	hypothetical protein	-
IF757_RS09405	1872734..1874380	+	1647	WP_000277741.1	IS1182-like element ISSau3 family transposase	-
-	1874694..1874749	+	56	-	-	Antitoxin
IF757_RS09415	1874806..1874910	-	105	WP_073392962.1	hypothetical protein	Toxin
IF757_RS09420	1875590..1875748	+	159	WP_001792784.1	hypothetical protein	-
IF757_RS09425	1876407..1877264	-	858	WP_000370937.1	HAD family hydrolase	-
IF757_RS09430	1877332..1878114	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1872734..1874380	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T174943 WP_073392962.1 NZ_CP062404:c1874910-1874806 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T174943 NZ_CP081713:769369-769746 [Escherichia coli]
ATGCAAACCCAACCACTATCCTCAACTCAGGAGGCTACACCACGCCCGTCACCGGTGGAGATCTGGCAACGGCTTCTGAG
CCACCTGTTGGATCGTCACTACGGTCTGACACTCAACGACACTCCGTTCGGCAACGATGGCGTGATTCAGGAGCATATCG
ACGCCGGTATCTCACTGTGCGACGCGGTGAATTTTATCGTGGAGAAATACGATCTGGTACGAACCGACCGTCGCGGTTTT
AACGCAGAAACACAGTCGCCTCTTCTCAGCAGTATCGATATTCTCCGCGCCCGCAAAGCCACCGGACTGATGACCCGAAA
CGATTACAGAACGGTGACCGACATCACCACCGGTAAATACCGGGAGGTGCAGCCATGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT174943 NZ_CP062404:1874694-1874749 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin