Detailed information of TA system TA174938

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1570616..1570796
• Replicon: chromosome
• Accession: NZ_CP062404
• Organism: Staphylococcus aureus strain NAS_NP_229

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF757_RS07685
• Protein ID: WP_001801861.1
• Coordinates: 1570616..1570711 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1570739..1570796 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF757_RS07655	1565760..1566386	+	627	WP_000669038.1	hypothetical protein	-
IF757_RS07660	1566427..1566771	+	345	WP_000627550.1	DUF3969 family protein	-
IF757_RS07665	1566869..1567441	+	573	WP_000414222.1	hypothetical protein	-
IF757_RS07670	1567590..1568957	-	1368	WP_001093574.1	FRG domain-containing protein	-
IF757_RS07675	1568957..1569526	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
IF757_RS07680	1569719..1570165	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
IF757_RS07685	1570616..1570711	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1570739..1570796	-	58	-	-	Antitoxin
IF757_RS07690	1570834..1570935	+	102	WP_001791232.1	hypothetical protein	-
IF757_RS07695	1571110..1571553	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
IF757_RS07700	1571553..1571996	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
IF757_RS07705	1571996..1572438	-	443	Protein_1516	DUF1433 domain-containing protein	-
IF757_RS07710	1572963..1575383	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174938 WP_001801861.1 NZ_CP062404:1570616-1570711 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174938 NZ_CP081712:35713-36093 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAGCCGCTACGGCGGCCTGCCGGGAATGTC
AGATCCGGGCAGGGCAGAGGCCATTATCGGGAGAGTCCAGGCCAGAGTTGTGTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACTGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGTTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACTGTAGGCGCTGCGACCGG
AGAGATATCTGTATCTTCTGTCGCCGACACGTTACGTAGATTGTATGGTTCCGCGGAGTAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT174938 NZ_CP062404:c1570796-1570739 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin