Detailed information of TA system TA174907

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1813180..1813360
• Replicon: chromosome
• Accession: NZ_CP062402
• Organism: Staphylococcus aureus strain NAS_OP_056

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF766_RS08635
• Protein ID: WP_001801861.1
• Coordinates: 1813180..1813275 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1813303..1813360 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF766_RS08600 (IF766_08565)	1808221..1808847	+	627	WP_000669021.1	hypothetical protein	-
IF766_RS08605 (IF766_08570)	1808888..1809229	+	342	WP_000627547.1	DUF3969 family protein	-
IF766_RS08610 (IF766_08575)	1809330..1809902	+	573	WP_000414206.1	hypothetical protein	-
IF766_RS08615 (IF766_08580)	1810100..1810728	-	629	Protein_1697	ImmA/IrrE family metallo-endopeptidase	-
IF766_RS08620 (IF766_08585)	1811028..1811204	-	177	WP_000375476.1	hypothetical protein	-
IF766_RS08625 (IF766_08590)	1811215..1811598	-	384	WP_000070811.1	hypothetical protein	-
IF766_RS08630 (IF766_08595)	1812283..1812729	-	447	WP_000747802.1	DUF1433 domain-containing protein	-
IF766_RS08635 (IF766_08600)	1813180..1813275	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1813303..1813360	-	58	-	-	Antitoxin
IF766_RS08640 (IF766_08605)	1813398..1813499	+	102	WP_001791232.1	hypothetical protein	-
IF766_RS08645 (IF766_08610)	1813477..1813659	-	183	Protein_1703	transposase	-
IF766_RS08650 (IF766_08615)	1813847..1814221	-	375	WP_000695818.1	DUF1433 domain-containing protein	-
IF766_RS08655 (IF766_08620)	1814243..1814521	-	279	WP_001798632.1	DUF1433 domain-containing protein	-
IF766_RS08660 (IF766_08625)	1814827..1815243	-	417	WP_020978241.1	DUF1433 domain-containing protein	-
IF766_RS08665 (IF766_08630)	1815891..1817009	-	1119	WP_000072558.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1805663..1851217	45554

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174907 WP_001801861.1 NZ_CP062402:1813180-1813275 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174907 NZ_CP081706:1087118-1087453 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAAGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGTCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT174907 NZ_CP062402:c1813360-1813303 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin