Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 2638356..2638634 | Replicon | chromosome |
Accession | NZ_CP062401 | ||
Organism | Staphylococcus aureus strain NAS_OP_098 |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | Q2FWA7 |
Locus tag | IF770_RS13080 | Protein ID | WP_001802298.1 |
Coordinates | 2638356..2638460 (+) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF3 | ||
Locus tag | - | ||
Coordinates | 2638456..2638634 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IF770_RS13065 | 2635153..2635935 | + | 783 | WP_000908182.1 | ABC transporter ATP-binding protein | - |
IF770_RS13070 | 2636003..2636860 | + | 858 | WP_000370925.1 | Cof-type HAD-IIB family hydrolase | - |
IF770_RS13075 | 2637518..2637676 | - | 159 | WP_001792784.1 | hypothetical protein | - |
IF770_RS13080 | 2638356..2638460 | + | 105 | WP_001802298.1 | hypothetical protein | Toxin |
- | 2638456..2638634 | - | 179 | - | - | Antitoxin |
IF770_RS13090 | 2638893..2639984 | - | 1092 | WP_000495669.1 | hypothetical protein | - |
IF770_RS13095 | 2640250..2641227 | - | 978 | WP_000019734.1 | CDF family zinc efflux transporter CzrB | - |
IF770_RS13100 | 2641229..2641549 | - | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
IF770_RS13105 | 2641701..2642366 | + | 666 | WP_001024095.1 | SDR family oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T174899 WP_001802298.1 NZ_CP062401:2638356-2638460 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T174899 NZ_CP081706:187027-187134 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
Antitoxin
Download Length: 179 bp
>AT174899 NZ_CP062401:c2638634-2638456 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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