Detailed information of TA system TA174825

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 180399..180581
• Replicon: chromosome
• Accession: NZ_CP062393
• Organism: Staphylococcus aureus strain NAS_AN_009

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF695_RS01080
• Protein ID: WP_001801861.1
• Coordinates: 180486..180581 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	180399..180458 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF695_RS01065	179537..179914	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
IF695_RS01070	180108..180284	+	177	Protein_177	transposase	-
IF695_RS01075	180262..180363	-	102	WP_001791893.1	hypothetical protein	-
-	180399..180458	+	60	-	-	Antitoxin
IF695_RS01080	180486..180581	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF695_RS01085	180784..180927	+	144	WP_001549059.1	transposase	-
IF695_RS01090	181531..181914	+	384	WP_000070811.1	hypothetical protein	-
IF695_RS01095	181925..182101	+	177	WP_000375476.1	hypothetical protein	-
IF695_RS01100	182103..182288	+	186	WP_000809857.1	hypothetical protein	-
IF695_RS01105	182402..183043	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
IF695_RS01110	183261..183812	-	552	WP_000414205.1	hypothetical protein	-
IF695_RS01115	183910..184254	-	345	WP_000627551.1	DUF3969 family protein	-
IF695_RS01120	184295..184921	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174825 WP_001801861.1 NZ_CP062393:c180581-180486 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174825 NZ_CP081685:c273702-273397 [Escherichia coli]
ATGCAATTCATCATCTACGAATATAAGCGGGTAAGCCATTACAAAATGTTTGTCGATGTGCAAAGCGATATAGTTGATAC
ACCAGGCCGTCGTATGGTTATACCGCTGATTGAATCCCATCACTTGTCTGAAATCGTAAACAGCTCCCTGTTCCCGGTAG
TCAGAATTAACGATGAAGACTACCGGGTAATGACTACCGAGCTATCAAGCGTGTCTGCGGCGGTTACTGGTGAAGCTATT
GCCGATGTCAGCTCTGATGCAGATGCGATAAAAAATGCTATCAACCTTATGTTCTGGGGAATTTAA

Antitoxin

Nucleotide

• Length: 60 bp

>AT174825 NZ_CP062393:180399-180458 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin