Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2344731..2344915 Replicon chromosome
Accession NZ_CP062390
Organism Staphylococcus aureus strain NAS_AN_036

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag IF699_RS11525 Protein ID WP_072467491.1
Coordinates 2344731..2344838 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2344855..2344915 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF699_RS11500 2340104..2340577 + 474 WP_000456489.1 GyrI-like domain-containing protein -
IF699_RS11505 2340700..2341911 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
IF699_RS11510 2342093..2342752 - 660 WP_000831298.1 membrane protein -
IF699_RS11515 2342812..2343954 - 1143 WP_001176873.1 glycerate kinase -
IF699_RS11520 2344211..2344597 + 387 WP_000779348.1 flippase GtxA -
IF699_RS11525 2344731..2344838 + 108 WP_072467491.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2344855..2344915 - 61 - - Antitoxin
IF699_RS11530 2345428..2347191 + 1764 WP_240024552.1 ABC transporter ATP-binding protein -
IF699_RS11535 2347216..2348949 + 1734 WP_000486502.1 ABC transporter ATP-binding protein -
IF699_RS11540 2349180..2349347 + 168 WP_031866196.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3944.67 Da        Isoelectric Point: 10.4934

>T174811 WP_072467491.1 NZ_CP062390:2344731-2344838 [Staphylococcus aureus]
IFNLLIDIMTSAISGCLVAFFANWLRTRSNKKGDK

Download         Length: 108 bp

>T174811 NZ_CP081684:2241995-2242098 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 61 bp

>AT174811 NZ_CP062390:c2344915-2344855 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References