Detailed information of TA system TA174807

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 166763..166943
• Replicon: chromosome
• Accession: NZ_CP062390
• Organism: Staphylococcus aureus strain NAS_AN_036

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF699_RS01055
• Protein ID: WP_001801861.1
• Coordinates: 166848..166943 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	166763..166820 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF699_RS01025	163114..164232	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
IF699_RS01030	164880..165323	+	444	WP_000742594.1	DUF1433 domain-containing protein	-
IF699_RS01035	165551..165880	+	330	WP_223294405.1	DUF1433 domain-containing protein	-
IF699_RS01040	165902..166276	+	375	WP_000695818.1	DUF1433 domain-containing protein	-
IF699_RS01045	166464..166646	+	183	Protein_170	transposase	-
IF699_RS01050	166624..166725	-	102	WP_001791232.1	hypothetical protein	-
-	166763..166820	+	58	-	-	Antitoxin
IF699_RS01055	166848..166943	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF699_RS01060	167394..167840	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
IF699_RS01065	168525..168908	+	384	WP_000070811.1	hypothetical protein	-
IF699_RS01070	168919..169095	+	177	WP_000375476.1	hypothetical protein	-
IF699_RS01075	169395..170023	+	629	Protein_176	ImmA/IrrE family metallo-endopeptidase	-
IF699_RS01080	170221..170793	-	573	Protein_177	hypothetical protein	-
IF699_RS01085	170894..171235	-	342	WP_000627548.1	DUF3969 family protein	-
IF699_RS01090	171276..171902	-	627	WP_000669019.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174807 WP_001801861.1 NZ_CP062390:c166943-166848 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174807 NZ_CP081684:1117928-1118239 [Escherichia coli]
ATGCACATCATTTCTAAAGCGCCATTTGAAGAGTCTGCGCGTAAATATCCTAACGACGCTCTGGCTCTTCAGGCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCCAACCTCGACAATTTTAGATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT174807 NZ_CP062390:166763-166820 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin