Detailed information of TA system TA174771

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 183322..183502
• Replicon: chromosome
• Accession: NZ_CP062386
• Organism: Staphylococcus aureus strain NAS_AN_047

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF701_RS01130
• Protein ID: WP_001801861.1
• Coordinates: 183407..183502 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	183322..183379 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF701_RS01100	179673..180791	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
IF701_RS01105	181439..181855	+	417	WP_020978241.1	DUF1433 domain-containing protein	-
IF701_RS01110	182161..182439	+	279	WP_001798632.1	DUF1433 domain-containing protein	-
IF701_RS01115	182461..182835	+	375	WP_000695818.1	DUF1433 domain-containing protein	-
IF701_RS01120	183023..183205	+	183	Protein_185	transposase	-
IF701_RS01125	183183..183284	-	102	WP_001791232.1	hypothetical protein	-
-	183322..183379	+	58	-	-	Antitoxin
IF701_RS01130	183407..183502	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF701_RS01135	183953..184399	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
IF701_RS01140	185084..185467	+	384	WP_000070811.1	hypothetical protein	-
IF701_RS01145	185478..185654	+	177	WP_000375476.1	hypothetical protein	-
IF701_RS01150	185954..186582	+	629	Protein_191	ImmA/IrrE family metallo-endopeptidase	-
IF701_RS01155	186780..187352	-	573	WP_000414206.1	hypothetical protein	-
IF701_RS01160	187453..187794	-	342	WP_000627547.1	DUF3969 family protein	-
IF701_RS01165	187835..188461	-	627	WP_000669021.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hlgA / lukD	156351..220195	63844

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174771 WP_001801861.1 NZ_CP062386:c183502-183407 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174771 NZ_CP081508:1944797-1944955 [Trueperella pyogenes]
GTGAAGATTCGGCAAACCGACGTGTATGCTCGCTGGTTTCGCAAGCTCAAAGATGTCCAGGGCACGGCCCGAATCAATAT
TGCACTTCAGCGTTGCAAAATAGCTGGCGAAGTAGTGGGTGACGTCAAGCCGGTTGGTGATGGCGTTTTTGAGATGTGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT174771 NZ_CP062386:183322-183379 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin