Detailed information of TA system TA174748

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2427364..2427548
• Replicon: chromosome
• Accession: NZ_CP062382
• Organism: Staphylococcus aureus strain NAS_AN_068

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: IF703_RS12065
• Protein ID: WP_000482647.1
• Coordinates: 2427364..2427471 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2427488..2427548 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF703_RS12040	2422735..2423208	+	474	WP_000456493.1	GyrI-like domain-containing protein	-
IF703_RS12045	2423331..2424542	-	1212	WP_001191927.1	multidrug effflux MFS transporter	-
IF703_RS12050	2424715..2425374	-	660	WP_031927729.1	membrane protein	-
IF703_RS12055	2425434..2426576	-	1143	WP_001176870.1	glycerate kinase	-
IF703_RS12060	2426844..2427230	+	387	WP_000779353.1	flippase GtxA	-
IF703_RS12065	2427364..2427471	+	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2427488..2427548	-	61	-	-	Antitoxin
IF703_RS12070	2428175..2429938	+	1764	WP_031927727.1	ABC transporter ATP-binding protein	-
IF703_RS12075	2429963..2431696	+	1734	WP_000486497.1	ABC transporter ATP-binding protein	-
IF703_RS12080	2431927..2432094	+	168	WP_031927726.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	2389246..2427771	38525

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T174748 WP_000482647.1 NZ_CP062382:2427364-2427471 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T174748 NZ_CP081490:c110155-109277 [Pseudomonas protegens]
ATGTTGCCAGGACGCTCTCAAGCGGCATCGACGGCCGACCTTCAAGCTCAGTTGGCTCGGGATTTTCCCCTGCAACGGGT
ATTGGCGGCCGGCGGCCAGCAGACCCTGCGCGAATGCGGCACGGGACCGGCCGTGGTGCTGCTGCACGGCATCGGTTCGG
CGGCCGCTTCTTGGCTGCAGGTCGCACAGCAGTTGGCTCCTAAGGCCCGGGTCATTGCTTGGGATGCGCCGGGCTACGGT
GAGTCCAGCCCCCTGGAATCACCTGCCCCCAAGGCCGAGCAATACGCCACCCGCCTCATGCAGATGCTCGATGCGCTGGA
TGTCGAGCAATGCGTGCTGGTCGGGCATTCCCTGGGCGCACTGCCGGCCCTGGCTTTCGCCCGCAGTTCGCAGGCGCCGC
GTGTGAGTCGCTTGCTGTTGATCAGTCCGACCCGGGGGTACGGCGCCTCGGAGCGGGCCCTGCAACGCCAGCAGGTGCGC
CAGCAACGCCTGGACAACTTGGAGCACCTGGGGATCGCGGGCCTGGCCGACCAACGCACCGCTCACATGTTGTCAGCCAA
CGCCGCGCCGCGCGCGCTGGCCTGGGTGCACTGGAACATGGCACGCCTGAACCCCGCCGGGTATCGCCAGGCCATCGAGC
TGCTGTGCGGCGACGACCTGCTGCGCCATGGCCCACCCGACATGCCCTGCGAAGTGCATTGCGGCGAATTCGACCGCATC
ACCCCCGCCCAGACCTGCCTGACCCTGGCCAAGGCGCTGGGCGCCAGCTTCAACCTGATCGCCGACGCGGGACACGCCAG
CCCCGTCGAACAACCGTTGGTGGTGGCGGGCCGCCTGGCCTTTGCCATCAAAGAATCCATGACAGGTAGACCCCTATGA

Antitoxin

Nucleotide

• Length: 61 bp

>AT174748 NZ_CP062382:c2427548-2427488 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin