Detailed information of TA system TA174713

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1842328..1842544
• Replicon: chromosome
• Accession: NZ_CP062378
• Organism: Staphylococcus aureus strain NAS_AN_079

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: IF705_RS09310
• Protein ID: WP_001802298.1
• Coordinates: 1842440..1842544 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1842328..1842383 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF705_RS09285	1838534..1839199	-	666	WP_001024095.1	SDR family oxidoreductase	-
IF705_RS09290	1839351..1839671	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
IF705_RS09295	1839673..1840650	+	978	WP_000019734.1	CDF family zinc efflux transporter CzrB	-
IF705_RS09300	1840916..1842007	+	1092	WP_000495669.1	hypothetical protein	-
-	1842328..1842383	+	56	-	-	Antitoxin
IF705_RS09310	1842440..1842544	-	105	WP_001802298.1	hypothetical protein	Toxin
IF705_RS09315	1843061..1843231	+	171	WP_001792292.1	transposase	-
IF705_RS09320	1843224..1843382	+	159	WP_001792784.1	hypothetical protein	-
IF705_RS09325	1844040..1844897	-	858	WP_000370925.1	Cof-type HAD-IIB family hydrolase	-
IF705_RS09330	1844965..1845747	-	783	WP_000908182.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T174713 WP_001802298.1 NZ_CP062378:c1842544-1842440 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T174713 NZ_CP081457:c6079312-6079022 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
ATGACTTATAGCCTCGAATTTGATGCGCGAGCTCTGAAGGAATGGCACAAATTAGGCGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCAAATCGCCTGCATGCGTTGCCCGACTGCTACAAAATCA
AGCTGCGCAGCAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGATGAGGTTTACCGTAAGGCGGCTGATCGGTTGGGTGGGTAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT174713 NZ_CP062378:1842328-1842383 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin