Detailed information of TA system TA174708

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1558956..1559136
• Replicon: chromosome
• Accession: NZ_CP062378
• Organism: Staphylococcus aureus strain NAS_AN_079

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF705_RS07710
• Protein ID: WP_001801861.1
• Coordinates: 1558956..1559051 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1559079..1559136 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF705_RS07680	1554119..1554769	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
IF705_RS07685	1554850..1555845	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
IF705_RS07690	1555920..1556546	+	627	WP_000669024.1	hypothetical protein	-
IF705_RS07695	1556587..1556928	+	342	WP_000627540.1	DUF3969 family protein	-
IF705_RS07700	1557029..1557601	+	573	WP_000414216.1	hypothetical protein	-
IF705_RS07705	1557799..1558811	-	1013	Protein_1515	IS3 family transposase	-
IF705_RS07710	1558956..1559051	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1559079..1559136	-	58	-	-	Antitoxin
IF705_RS07715	1559174..1559275	+	102	WP_001792025.1	hypothetical protein	-
IF705_RS07720	1559253..1559414	-	162	Protein_1518	transposase	-
IF705_RS07725	1559399..1559809	-	411	WP_001808705.1	IS21 family transposase	-
IF705_RS07730	1560351..1561580	-	1230	WP_000072627.1	restriction endonuclease subunit S	-
IF705_RS07735	1561573..1563129	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
IF705_RS07740	1563293..1563427	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174708 WP_001801861.1 NZ_CP062378:1558956-1559051 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174708 NZ_CP081457:4399718-4400068 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
ATGAATACGTTTGCACTGAGCTTTACTGATGTTGCTCAGCAAAGCCTCGAAGATCAGGTTGAACACCTGGCTGTCACTCA
GGGATTCTCATCAGCGGCTCAACGCATAGATACCCTGATTGATGCCATCCAGGATAAGCTCATATCCACCCCGTTGGGCT
ACCCGGTCAGTCCTCAATTGAGTGAGCTGGGCGTACTGCACTATCGTGAGTTGAACACAGACGGATACCGGATCTTTTAC
GAGGTCATGGATTCTGATGGTATTACCGACATCGCCGTATTGCTCGTATTAGGCGGGAAAAAAAGTGTTGAACAAGCCCT
GATCCGCTATTGCCTTCTTCAGCCTATATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT174708 NZ_CP062378:c1559136-1559079 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin