Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2303054..2303238 Replicon chromosome
Accession NZ_CP062376
Organism Staphylococcus aureus strain NAS_AN_099

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag IF707_RS11135 Protein ID WP_000482647.1
Coordinates 2303054..2303161 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2303178..2303238 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF707_RS11110 2298416..2298889 + 474 WP_000456489.1 GyrI-like domain-containing protein -
IF707_RS11115 2299012..2300223 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
IF707_RS11120 2300405..2301064 - 660 WP_000831298.1 membrane protein -
IF707_RS11125 2301124..2302266 - 1143 WP_001176863.1 glycerate kinase -
IF707_RS11130 2302534..2302920 + 387 WP_000779360.1 flippase GtxA -
IF707_RS11135 2303054..2303161 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2303178..2303238 - 61 - - Antitoxin
IF707_RS11140 2303868..2305631 + 1764 WP_006191000.1 ABC transporter ATP-binding protein -
IF707_RS11145 2305656..2307389 + 1734 WP_000486494.1 ABC transporter ATP-binding protein -
IF707_RS11150 2307620..2307787 + 168 WP_001790576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T174694 WP_000482647.1 NZ_CP062376:2303054-2303161 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T174694 NZ_CP081354:c888058-887870 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTAGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 61 bp

>AT174694 NZ_CP062376:c2303238-2303178 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References